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clofarabine

Synonyms

SourcesNames Used
CTRPv2clofarabine
PharmacoGx clofarabine

External IDs

DatabaseIdentifier
Smiles: Nc1nc(Cl)nc2n(cnc12)C3OC(CO)C(O)C3F
Inchikey: WDDPHFBMKLOVOX-UHFFFAOYSA-N
Pubchem: 119182

Annotated Targets

POLA1, POLD1, POLE, RRM1, RRM2, RRM2B

FDA Approval Status

Approved
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Top molecular features associated with response to clofarabine


Feature TypeStandardized
Nominal ANOVA
mRNA SELT CTRPv2 pan-cancer AAC -0.093 0.001
mRNA BRD7 CTRPv2 pan-cancer AAC 0.095 0.001
mRNA DKK3 CTRPv2 pan-cancer AAC -0.12 0.001
mRNA MARS2 CTRPv2 pan-cancer AAC 0.11 0.001
mRNA STIM1 CTRPv2 pan-cancer AAC -0.096 0.001
mRNA RNF103 CTRPv2 pan-cancer AAC -0.095 0.001
mRNA JPH2 CTRPv2 pan-cancer AAC -0.097 0.001
mRNA RFC3 CTRPv2 pan-cancer AAC 0.097 0.001
mRNA C3orf62 CTRPv2 pan-cancer AAC 0.1 0.001
mRNA CPNE7 CTRPv2 pan-cancer AAC 0.097 0.001
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