About
Documentation
Cite Us!
Github
Download
News
Explore
Batch Query
Search
Site
Home
About
Documentation
PharmacoGx
Cite Us!
Tools
Explore
Batch Query
Search
GitHub
Datatypes
datasets
cell lines
tissues
drugs
genes
experiments
Home
/
Compounds
/
JQ-1:MK-0752 (1:1 mol/mol)
JQ-1:MK-0752 (1:1 mol/mol)
Synonyms
Sources
Names Used
CTRPv2
JQ-1:MK-0752 (1:1 mol/mol)
PharmacoGx
JQ-1:MK-0752 (1:1 mol/mol)
FDA Approval Status
Not Approved
Plots
Cell Line Summary
Tissue Summary
Molecular Features
Number of cell lines tested with
JQ-1:MK-0752 (1:1 mol/mol) (per dataset)
0
100
200
300
400
500
600
700
800
# cell lines
CCLE
GDSC1000
gCSI
GRAY
FIMM
UHNBreast
CTRPv2
0
0
0
0
0
0
811
Download SVG
Number of tissues tested with
JQ-1:MK-0752 (1:1 mol/mol) (per dataset)
0
2
4
6
8
10
12
14
16
18
20
22
24
# tissues
CCLE
GDSC1000
gCSI
GRAY
FIMM
UHNBreast
CTRPv2
0
0
0
0
0
0
25
Download SVG
Dataset Select
all
CTRPv2
JQ-1:MK-0752 (1:1 mol/mol): AAC
AAC
0.00
0.10
0.20
0.30
0.40
0.50
0.60
0.70
0.80
SU-DHL-6
SU-DHL-6
KMS-26
KMS-26
SNU-466
SNU-466
AM-38
AM-38
KMS-12-BM
KMS-12-BM
GSS
GSS
KMS-27
KMS-27
SEM
SEM
OCI-AML3
OCI-AML3
NCI-H1734
NCI-H1734
HCC-44
HCC-44
HCC1569
HCC1569
YD-15
YD-15
NCI-H211
NCI-H211
COR-L88
COR-L88
HEL
HEL
THP-1
THP-1
SNU-1079
SNU-1079
YD-38
YD-38
KASUMI-1
KASUMI-1
NALM-6
NALM-6
KHM-1B
KHM-1B
Set-2
Set-2
EoL-1-cell
EoL-1-cell
KMS-21BM
KMS-21BM
NCI-H23
NCI-H23
EM-2
EM-2
SK-MM-2
SK-MM-2
MOLM-13
MOLM-13
KMS-11
KMS-11
BT359
BT359
SNU-410
SNU-410
NCI-H838
NCI-H838
Calu-1
Calu-1
HEC-265
HEC-265
NCI-H1563
NCI-H1563
ES-2
ES-2
HCC2935
HCC2935
Hs 688(A).T
Hs 688(A).T
Hs 822.T
Hs 822.T
CAL-120
CAL-120
KYSE-150
KYSE-150
HT-29
HT-29
639-V
639-V
NCI-H1092
NCI-H1092
BT320
BT320
Calu-6
Calu-6
DOV13
DOV13
TE 441.T
TE 441.T
PLC-PRF-5
PLC-PRF-5
SNU-C4
SNU-C4
MEL-JUSO
MEL-JUSO
NCI-H889
NCI-H889
NCI-H2122
NCI-H2122
SBC-5
SBC-5
BT328
BT328
PC-3
PC-3
BT16
BT16
HEC-108
HEC-108
MKN45
MKN45
SU-DHL-6
KMS-26
SNU-466
AM-38
KMS-12-BM
GSS
KMS-27
SEM
OCI-AML3
NCI-H1734
HCC-44
HCC1569
YD-15
NCI-H211
COR-L88
HEL
THP-1
SNU-1079
YD-38
KASUMI-1
NALM-6
KHM-1B
Set-2
EoL-1-cell
KMS-21BM
NCI-H23
EM-2
SK-MM-2
MOLM-13
KMS-11
BT359
SNU-410
NCI-H838
Calu-1
HEC-265
NCI-H1563
ES-2
HCC2935
Hs 688(A).T
Hs 822.T
CAL-120
KYSE-150
HT-29
639-V
NCI-H1092
BT320
Calu-6
DOV13
TE 441.T
PLC-PRF-5
SNU-C4
MEL-JUSO
NCI-H889
NCI-H2122
SBC-5
BT328
PC-3
BT16
HEC-108
MKN45
SU-DHL-6: 0.85
Synonyms: SU-DHL-6, SUDHL6
KMS-26: 0.78
Synonyms: KMS-26, KMS26
SNU-466: 0.76
Synonyms: SNU-466, SNU466
AM-38: 0.69
Synonyms: AM-38, AM38
KMS-12-BM: 0.64
Synonyms: KMS-12-BM, KMS12BM
GSS: 0.63
Synonyms: GSS
KMS-27: 0.63
Synonyms: KMS-27, KMS27
SEM: 0.63
Synonyms: SEM
OCI-AML3: 0.63
Synonyms: OCI-AML3, OCIAML3
NCI-H1734: 0.61
Synonyms: NCI-H1734, NCIH1734
HCC-44: 0.57
Synonyms: HCC-44, HCC44
HCC1569: 0.57
Synonyms: HCC1569, hcc1569
YD-15: 0.57
Synonyms: YD-15, YD15
NCI-H211: 0.57
Synonyms: NCI-H211, NCIH211
COR-L88: 0.57
Synonyms: COR-L88, CORL88
HEL: 0.56
Synonyms: HEL
THP-1: 0.56
Synonyms: THP-1, THP1
SNU-1079: 0.56
Synonyms: SNU-1079, SNU1079
YD-38: 0.54
Synonyms: YD-38, YD38
KASUMI-1: 0.54
Synonyms: KASUMI-1, Kasumi-1, KASUMI1
NALM-6: 0.54
Synonyms: NALM-6, NALM6
KHM-1B: 0.54
Synonyms: KHM-1B, KHM1B
Set-2: 0.53
Synonyms: Set-2, Set2, SET-2, SET2
EoL-1-cell: 0.53
Synonyms: EoL-1-cell, EOL-1, EOL1
KMS-21BM: 0.52
Synonyms: KMS-21BM, KMS21BM
NCI-H23: 0.52
Synonyms: NCI-H23, NCIH23
EM-2: 0.52
Synonyms: EM-2, EM2
SK-MM-2: 0.51
Synonyms: SK-MM-2, SKMM2
MOLM-13: 0.51
Synonyms: MOLM-13, MOLM13
KMS-11: 0.51
Synonyms: KMS-11, KMS11
: 0.00
Synonyms:
: 0.00
Synonyms:
: 0.00
Synonyms:
: 0.00
Synonyms:
: 0.00
Synonyms:
BT359: 0.04
Synonyms: BT359
SNU-410: 0.03
Synonyms: SNU-410, SNU410
NCI-H838: 0.03
Synonyms: NCI-H838, NCIH838
Calu-1: 0.03
Synonyms: Calu-1, CALU1
HEC-265: 0.03
Synonyms: HEC-265, HEC265
NCI-H1563: 0.03
Synonyms: NCI-H1563, NCIH1563
ES-2: 0.03
Synonyms: ES-2, ES2
HCC2935: 0.03
Synonyms: HCC2935
Hs 688(A).T: 0.02
Synonyms: Hs 688(A).T, Hs_688_A_.T, HS688AT
Hs 822.T: 0.02
Synonyms: Hs 822.T, Hs_822.T, HS822T
CAL-120: 0.02
Synonyms: CAL-120, CAL120, cal120
KYSE-150: 0.02
Synonyms: KYSE-150, KYSE150
HT-29: 0.02
Synonyms: HT-29, HT29
639-V: 0.02
Synonyms: 639-V, 639V
NCI-H1092: 0.02
Synonyms: NCI-H1092, NCIH1092
BT320: 0.02
Synonyms: BT320
Calu-6: 0.02
Synonyms: Calu-6, CALU6
DOV13: 0.01
Synonyms: DOV13
TE 441.T: 0.01
Synonyms: TE 441.T, TE_441.T, TE-441-T, TE441T
PLC-PRF-5: 0.01
Synonyms: PLC-PRF-5, PLC/PRF/5, PLC_PRF_5, PLCPRF5
SNU-C4: 0.01
Synonyms: SNU-C4, SNUC4
MEL-JUSO: 0.01
Synonyms: MEL-JUSO, MELJUSO
NCI-H889: 0.01
Synonyms: NCI-H889, NCIH889
NCI-H2122: 0.01
Synonyms: NCI-H2122, NCIH2122
SBC-5: 0.00
Synonyms: SBC-5, SBC5
BT328: 0.00
Synonyms: BT328
PC-3: 0.00
Synonyms: PC-3, PC3
BT16: 0.00
Synonyms: BT16
HEC-108: 0.00
Synonyms: HEC-108, HEC108
MKN45: 0.00
Synonyms: MKN45, MKN-45
Download SVG
0.00
5.00
10.00
15.00
20.00
25.00
30.00
35.00
LN-18
LN-18
KNS-60
KNS-60
HCT-116
HCT-116
PC-14
PC-14
CAL-51
CAL-51
HCC1395
HCC1395
CCF-STTG1
CCF-STTG1
HS578BST
HS578BST
Hs 934.T
Hs 934.T
HT-29
HT-29
KP-N-YN
KP-N-YN
AN3-CA
AN3-CA
CAL-29
CAL-29
EC-GI-10
EC-GI-10
BT245
BT245
A253
A253
Hs 729
Hs 729
Caki-2
Caki-2
NCI-H2452
NCI-H2452
JIMT-1
JIMT-1
BT131
BT131
PSN1
PSN1
FADU
FADU
BT333
BT333
JHH-1
JHH-1
SNU-1077
SNU-1077
JVM-2
JVM-2
BT330
BT330
NCI-H1650
NCI-H1650
DU-145
DU-145
MOLP-8
MOLP-8
NCI-H23
NCI-H23
Set-2
Set-2
MOLM-16
MOLM-16
KASUMI-1
KASUMI-1
MOLM-13
MOLM-13
EM-2
EM-2
OPM-2
OPM-2
KMS-21BM
KMS-21BM
SK-MM-2
SK-MM-2
KMS-11
KMS-11
HCC-44
HCC-44
EoL-1-cell
EoL-1-cell
SNU-1079
SNU-1079
NALM-6
NALM-6
THP-1
THP-1
OCI-AML3
OCI-AML3
COR-L88
COR-L88
SNU-5
SNU-5
SEM
SEM
GSS
GSS
KMS-12-BM
KMS-12-BM
SNU-1214
SNU-1214
YD-38
YD-38
NCI-H1734
NCI-H1734
HCC1569
HCC1569
KMS-26
KMS-26
KMS-27
KMS-27
YD-15
YD-15
SNU-466
SNU-466
LN-18
KNS-60
HCT-116
PC-14
CAL-51
HCC1395
CCF-STTG1
HS578BST
Hs 934.T
HT-29
KP-N-YN
AN3-CA
CAL-29
EC-GI-10
BT245
A253
Hs 729
Caki-2
NCI-H2452
JIMT-1
BT131
PSN1
FADU
BT333
JHH-1
SNU-1077
JVM-2
BT330
NCI-H1650
DU-145
MOLP-8
NCI-H23
Set-2
MOLM-16
KASUMI-1
MOLM-13
EM-2
OPM-2
KMS-21BM
SK-MM-2
KMS-11
HCC-44
EoL-1-cell
SNU-1079
NALM-6
THP-1
OCI-AML3
COR-L88
SNU-5
SEM
GSS
KMS-12-BM
SNU-1214
YD-38
NCI-H1734
HCC1569
KMS-26
KMS-27
YD-15
SNU-466
LN-18: 35.12 (log10 µM)
Synonyms: LN-18, LN18
KNS-60: 8.58 (log10 µM)
Synonyms: KNS-60, KNS60
HCT-116: 6.62 (log10 µM)
Synonyms: HCT-116, HCT 116, HCT_116, HCT116
PC-14: 5.68 (log10 µM)
Synonyms: PC-14, PC14
CAL-51: 5.56 (log10 µM)
Synonyms: CAL-51, CAL51, cal51
HCC1395: 5.25 (log10 µM)
Synonyms: HCC1395, hcc1395
CCF-STTG1: 4.97 (log10 µM)
Synonyms: CCF-STTG1, CCFSTTG1
HS578BST: 4.84 (log10 µM)
Synonyms: HS578BST
Hs 934.T: 4.65 (log10 µM)
Synonyms: Hs 934.T, Hs_934.T, HS934T
HT-29: 4.42 (log10 µM)
Synonyms: HT-29, HT29
KP-N-YN: 4.39 (log10 µM)
Synonyms: KP-N-YN, KPNYN
AN3-CA: 4.34 (log10 µM)
Synonyms: AN3-CA, AN3 CA, AN3_CA, AN3CA
CAL-29: 4.29 (log10 µM)
Synonyms: CAL-29, CAL29
EC-GI-10: 4.26 (log10 µM)
Synonyms: EC-GI-10, ECGI10
BT245: 4.25 (log10 µM)
Synonyms: BT245
A253: 4.01 (log10 µM)
Synonyms: A253, A-253
Hs 729: 3.71 (log10 µM)
Synonyms: Hs 729, Hs_729, HS729
Caki-2: 3.60 (log10 µM)
Synonyms: Caki-2, CAKI2
NCI-H2452: 3.56 (log10 µM)
Synonyms: NCI-H2452, NCIH2452
JIMT-1: 3.49 (log10 µM)
Synonyms: JIMT-1, JIMT1, jimt1
BT131: 3.46 (log10 µM)
Synonyms: BT131
PSN1: 3.45 (log10 µM)
Synonyms: PSN1
FADU: 3.30 (log10 µM)
Synonyms: FADU, FaDu
BT333: 3.22 (log10 µM)
Synonyms: BT333
JHH-1: 3.21 (log10 µM)
Synonyms: JHH-1, JHH1
SNU-1077: 3.12 (log10 µM)
Synonyms: SNU-1077, SNU1077
JVM-2: 3.02 (log10 µM)
Synonyms: JVM-2, JVM2
BT330: 2.92 (log10 µM)
Synonyms: BT330
NCI-H1650: 2.91 (log10 µM)
Synonyms: NCI-H1650, NCIH1650
DU-145: 2.90 (log10 µM)
Synonyms: DU-145, DU 145, DU_145, DU145
: 0.00 (log10 µM)
Synonyms:
: 0.00 (log10 µM)
Synonyms:
: 0.00 (log10 µM)
Synonyms:
: 0.00 (log10 µM)
Synonyms:
: 0.00 (log10 µM)
Synonyms:
MOLP-8: -0.53 (log10 µM)
Synonyms: MOLP-8, MOLP8
NCI-H23: -0.56 (log10 µM)
Synonyms: NCI-H23, NCIH23
Set-2: -0.59 (log10 µM)
Synonyms: Set-2, Set2, SET-2, SET2
MOLM-16: -0.64 (log10 µM)
Synonyms: MOLM-16, MOLM16
KASUMI-1: -0.65 (log10 µM)
Synonyms: KASUMI-1, Kasumi-1, KASUMI1
MOLM-13: -0.65 (log10 µM)
Synonyms: MOLM-13, MOLM13
EM-2: -0.67 (log10 µM)
Synonyms: EM-2, EM2
OPM-2: -0.69 (log10 µM)
Synonyms: OPM-2, OPM2
KMS-21BM: -0.70 (log10 µM)
Synonyms: KMS-21BM, KMS21BM
SK-MM-2: -0.71 (log10 µM)
Synonyms: SK-MM-2, SKMM2
KMS-11: -0.72 (log10 µM)
Synonyms: KMS-11, KMS11
HCC-44: -0.73 (log10 µM)
Synonyms: HCC-44, HCC44
EoL-1-cell: -0.74 (log10 µM)
Synonyms: EoL-1-cell, EOL-1, EOL1
SNU-1079: -0.74 (log10 µM)
Synonyms: SNU-1079, SNU1079
NALM-6: -0.75 (log10 µM)
Synonyms: NALM-6, NALM6
THP-1: -0.81 (log10 µM)
Synonyms: THP-1, THP1
OCI-AML3: -1.02 (log10 µM)
Synonyms: OCI-AML3, OCIAML3
COR-L88: -1.07 (log10 µM)
Synonyms: COR-L88, CORL88
SNU-5: -1.08 (log10 µM)
Synonyms: SNU-5, SNU5
SEM: -1.10 (log10 µM)
Synonyms: SEM
GSS: -1.25 (log10 µM)
Synonyms: GSS
KMS-12-BM: -1.26 (log10 µM)
Synonyms: KMS-12-BM, KMS12BM
SNU-1214: -1.54 (log10 µM)
Synonyms: SNU-1214, SNU1214
YD-38: -1.60 (log10 µM)
Synonyms: YD-38, YD38
NCI-H1734: -1.63 (log10 µM)
Synonyms: NCI-H1734, NCIH1734
HCC1569: -1.66 (log10 µM)
Synonyms: HCC1569, hcc1569
KMS-26: -1.66 (log10 µM)
Synonyms: KMS-26, KMS26
KMS-27: -1.68 (log10 µM)
Synonyms: KMS-27, KMS27
YD-15: -1.73 (log10 µM)
Synonyms: YD-15, YD15
SNU-466: -1.79 (log10 µM)
Synonyms: SNU-466, SNU466
AAC
pIC50
* Plot represents the top and bottom 30 data points
** Error Bars represent the Median Absolute Deviation
Download SVG
Download Data as CSV
JQ-1:MK-0752 (1:1 mol/mol): AAC
AAC
Tissues
0.00
0.10
0.20
0.30
0.40
0.50
0.60
0.70
0.80
cervix
cervix
kidney
kidney
pancreas
pancreas
oesophagus
oesophagus
liver
liver
unknown
unknown
urinary_tract
urinary_tract
skin
skin
pleura
pleura
breast
breast
central_nervous_system
central_nervous_system
prostate
prostate
endometrium
endometrium
thyroid
thyroid
lung
lung
ovary
ovary
bone
bone
large_intestine
large_intestine
upper_aerodigestive_tract
upper_aerodigestive_tract
soft_tissue
soft_tissue
autonomic_ganglia
autonomic_ganglia
biliary_tract
biliary_tract
stomach
stomach
haematopoietic_and_lymphoid_tissue
haematopoietic_and_lymphoid_tissue
salivary_gland
salivary_gland
-5.00
-4.00
-3.00
-2.00
-1.00
0.00
1.00
2.00
3.00
4.00
5.00
salivary_gland
salivary_gland
cervix
cervix
prostate
prostate
haematopoietic_and_lymphoid_tissue
haematopoietic_and_lymphoid_tissue
upper_aerodigestive_tract
upper_aerodigestive_tract
stomach
stomach
biliary_tract
biliary_tract
oesophagus
oesophagus
bone
bone
autonomic_ganglia
autonomic_ganglia
soft_tissue
soft_tissue
endometrium
endometrium
large_intestine
large_intestine
lung
lung
central_nervous_system
central_nervous_system
ovary
ovary
thyroid
thyroid
pancreas
pancreas
unknown
unknown
pleura
pleura
breast
breast
skin
skin
urinary_tract
urinary_tract
liver
liver
kidney
kidney
AAC
pIC50
= Truncated outliers
Download SVG
Top molecular features associated with response to JQ-1:MK-0752 (1:1 mol/mol)
Feature Type
Gene
Dataset
Tissue
Stat
Standardized
Coefficient
Nominal ANOVA
p-value
mRNA
LMNB1
CTRPv2
pan-cancer
AAC
0.11
0.002
mRNA
MDM4
CTRPv2
pan-cancer
AAC
0.12
0.002
mRNA
FOXRED2
CTRPv2
pan-cancer
AAC
0.11
0.002
mRNA
SFPQ
CTRPv2
pan-cancer
AAC
0.11
0.002
mRNA
TICAM2
CTRPv2
pan-cancer
AAC
-0.13
0.002
mRNA
MTNR1A
CTRPv2
pan-cancer
AAC
0.1
0.002
mRNA
AC009065.1
CTRPv2
pan-cancer
AAC
0.11
0.002
mRNA
ETNPPL
CTRPv2
pan-cancer
AAC
0.1
0.002
mRNA
SHF
CTRPv2
pan-cancer
AAC
0.12
0.002
mRNA
CNBD2
CTRPv2
pan-cancer
AAC
0.1
0.002
← Previous
1
2
…
35
36
37
…
199
200
Next →
Download CSV