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Compounds
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necrostatin-7
necrostatin-7
Synonyms
Sources
Names Used
CTRPv2
necrostatin-7
PharmacoGx
necrostatin-7
External IDs
Database
Identifier
Pubchem:
1239801
FDA Approval Status
Not Approved
Plots
Cell Line Summary
Tissue Summary
Molecular Features
Number of cell lines tested with
necrostatin-7 (per dataset)
0
100
200
300
400
500
600
700
800
# cell lines
CCLE
GDSC1000
gCSI
GRAY
FIMM
UHNBreast
CTRPv2
0
0
0
0
0
0
841
Download SVG
Number of tissues tested with
necrostatin-7 (per dataset)
0
2
4
6
8
10
12
14
16
18
20
22
24
# tissues
CCLE
GDSC1000
gCSI
GRAY
FIMM
UHNBreast
CTRPv2
0
0
0
0
0
0
25
Download SVG
Dataset Select
all
CTRPv2
necrostatin-7: AAC
AAC
0.00
0.05
0.10
0.15
0.20
0.25
0.30
0.35
CL-34
CL-34
SNU-761
SNU-761
NCI-H2444
NCI-H2444
SNG-M
SNG-M
SU.86.86
SU.86.86
UO31
UO31
TE-6
TE-6
GA-10
GA-10
EKVX
EKVX
OV7
OV7
KNS81
KNS81
KNS-60
KNS-60
NCI-H1355
NCI-H1355
NCI-H2087
NCI-H2087
TE-4
TE-4
SJSA-1
SJSA-1
PC-14
PC-14
NCI-H524
NCI-H524
NCI-H226
NCI-H226
Ishikawa (Heraklio) 02 ER-
Ishikawa (Heraklio) 02 ER-
KMS-34
KMS-34
HCC2218
HCC2218
CAL-12T
CAL-12T
DB
DB
SW 1271
SW 1271
SW620
SW620
NCI-H2228
NCI-H2228
697
697
DEL
DEL
NCI-H1666
NCI-H1666
YD-38
YD-38
Hs 766T
Hs 766T
HPAF-II
HPAF-II
A2058
A2058
WM1799
WM1799
NCI-H2009
NCI-H2009
NUGC-3
NUGC-3
YKG-1
YKG-1
SNU-886
SNU-886
SNU-201
SNU-201
JHOS-2
JHOS-2
KP-2
KP-2
HSC-3
HSC-3
BICR 16
BICR 16
CW-2
CW-2
NMC-G1
NMC-G1
CAL-120
CAL-120
CAL-62
CAL-62
QGP-1
QGP-1
KCL-22
KCL-22
TUHR10TKB
TUHR10TKB
MDA-MB-435
MDA-MB-435
MDST8
MDST8
OE19
OE19
U-118-MG
U-118-MG
IM-95
IM-95
Becker
Becker
RPMI-6666
RPMI-6666
A253
A253
CAL-27
CAL-27
CL-34
SNU-761
NCI-H2444
SNG-M
SU.86.86
UO31
TE-6
GA-10
EKVX
OV7
KNS81
KNS-60
NCI-H1355
NCI-H2087
TE-4
SJSA-1
PC-14
NCI-H524
NCI-H226
Ishikawa (Heraklio) 02 ER-
KMS-34
HCC2218
CAL-12T
DB
SW 1271
SW620
NCI-H2228
697
DEL
NCI-H1666
YD-38
Hs 766T
HPAF-II
A2058
WM1799
NCI-H2009
NUGC-3
YKG-1
SNU-886
SNU-201
JHOS-2
KP-2
HSC-3
BICR 16
CW-2
NMC-G1
CAL-120
CAL-62
QGP-1
KCL-22
TUHR10TKB
MDA-MB-435
MDST8
OE19
U-118-MG
IM-95
Becker
RPMI-6666
A253
CAL-27
CL-34: 0.38
Synonyms: CL-34, CL34
SNU-761: 0.36
Synonyms: SNU-761, SNU761
NCI-H2444: 0.35
Synonyms: NCI-H2444, NCIH2444
SNG-M: 0.32
Synonyms: SNG-M, SNGM
SU.86.86: 0.32
Synonyms: SU.86.86, SU8686
UO31: 0.29
Synonyms: UO31, UO-31, U031
TE-6: 0.29
Synonyms: TE-6, TE6
GA-10: 0.25
Synonyms: GA-10, GA10
EKVX: 0.23
Synonyms: EKVX
OV7: 0.22
Synonyms: OV7, OV-7
KNS81: 0.22
Synonyms: KNS81
KNS-60: 0.21
Synonyms: KNS-60, KNS60
NCI-H1355: 0.21
Synonyms: NCI-H1355, NCIH1355
NCI-H2087: 0.21
Synonyms: NCI-H2087, NCIH2087
TE-4: 0.20
Synonyms: TE-4, TE4
SJSA-1: 0.20
Synonyms: SJSA-1, SJSA1
PC-14: 0.20
Synonyms: PC-14, PC14
NCI-H524: 0.19
Synonyms: NCI-H524, NCIH524
NCI-H226: 0.18
Synonyms: NCI-H226, NCIH226
Ishikawa (Heraklio) 02 ER-: 0.18
Synonyms: Ishikawa (Heraklio) 02 ER-, Ishikawa__Heraklio__02_ER-, Ishikawa_Heraklio_02ER-, ISHIKAWAHERAKLIO02ER
KMS-34: 0.17
Synonyms: KMS-34, KMS34
HCC2218: 0.17
Synonyms: HCC2218, hcc2218
CAL-12T: 0.17
Synonyms: CAL-12T, CAL12T
DB: 0.17
Synonyms: DB
SW 1271: 0.17
Synonyms: SW 1271, SW_1271, SW1271
SW620: 0.17
Synonyms: SW620, SW 620
NCI-H2228: 0.16
Synonyms: NCI-H2228, NCIH2228
697: 0.16
Synonyms: 697
DEL: 0.16
Synonyms: DEL
NCI-H1666: 0.16
Synonyms: NCI-H1666, NCIH1666
: 0.00
Synonyms:
: 0.00
Synonyms:
: 0.00
Synonyms:
: 0.00
Synonyms:
: 0.00
Synonyms:
YD-38: 0.00
Synonyms: YD-38, YD38
Hs 766T: 0.00
Synonyms: Hs 766T, Hs_766T, Hs-766T, Hs766T, HS766T
HPAF-II: 0.00
Synonyms: HPAF-II, HPAFII
A2058: 0.00
Synonyms: A2058
WM1799: 0.00
Synonyms: WM1799
NCI-H2009: 0.00
Synonyms: NCI-H2009, NCIH2009
NUGC-3: 0.00
Synonyms: NUGC-3, NUGC3
YKG-1: 0.00
Synonyms: YKG-1, YKG1
SNU-886: 0.00
Synonyms: SNU-886, SNU886
SNU-201: 0.00
Synonyms: SNU-201, SNU201
JHOS-2: 0.00
Synonyms: JHOS-2, JHOS2
KP-2: 0.00
Synonyms: KP-2, KP2
HSC-3: 0.00
Synonyms: HSC-3, HSC3
BICR 16: 0.00
Synonyms: BICR 16, BICR_16, BICR16
CW-2: 0.00
Synonyms: CW-2, CW2
NMC-G1: 0.00
Synonyms: NMC-G1, NMCG1
CAL-120: 0.00
Synonyms: CAL-120, CAL120, cal120
CAL-62: 0.00
Synonyms: CAL-62, CAL62
QGP-1: 0.00
Synonyms: QGP-1, QGP1
KCL-22: 0.00
Synonyms: KCL-22, KCL22
TUHR10TKB: 0.00
Synonyms: TUHR10TKB
MDA-MB-435: 0.00
Synonyms: MDA-MB-435, MDA-MB-435S, MDAMB435S
MDST8: 0.00
Synonyms: MDST8
OE19: 0.00
Synonyms: OE19
U-118-MG: 0.00
Synonyms: U-118-MG, U-118 MG, U-118_MG, U118MG
IM-95: 0.00
Synonyms: IM-95, IM95
Becker: 0.00
Synonyms: Becker, BECKER
RPMI-6666: 0.00
Synonyms: RPMI-6666, RPMI6666
A253: 0.00
Synonyms: A253, A-253
CAL-27: 0.00
Synonyms: CAL-27, CAL 27, CAL_27, CAL27
Download SVG
0.00
2.00
4.00
6.00
8.00
10.00
12.00
14.00
SNU-308
SNU-308
NOMO-1
NOMO-1
Hs 294T
Hs 294T
MOLM-6
MOLM-6
L-363
L-363
Hs 940.T
Hs 940.T
RKO
RKO
NCI-H2228
NCI-H2228
CCK-81
CCK-81
Hs 888.T
Hs 888.T
TUHR14TKB
TUHR14TKB
SNU-503
SNU-503
HEC1B
HEC1B
LU-65
LU-65
SNU-46
SNU-46
GI-1
GI-1
NCI-H929
NCI-H929
ML-1
ML-1
M059K
M059K
SJSA-1
SJSA-1
KARPAS-422
KARPAS-422
TTTHYROID
TTTHYROID
BV-173
BV-173
NCI-H1755
NCI-H1755
Calu-1
Calu-1
BT328
BT328
KM12
KM12
KLE
KLE
SNU-216
SNU-216
PSTS
PSTS
KMS-26
KMS-26
COLO-668
COLO-668
A3-KAW
A3-KAW
NCI-H524
NCI-H524
P12-ICHIKAWA
P12-ICHIKAWA
MOLT-3
MOLT-3
Daudi
Daudi
LS-1034
LS-1034
RS4;11
RS4;11
EB1
EB1
SEM
SEM
KMS-12-BM
KMS-12-BM
A673
A673
SUP-M2
SUP-M2
L-428
L-428
EoL-1-cell
EoL-1-cell
DB
DB
697
697
DEL
DEL
NCI-H1155
NCI-H1155
LS-123
LS-123
MV-4-11
MV-4-11
KMS-18
KMS-18
KMS-34
KMS-34
WSU-DLCL2
WSU-DLCL2
SW620
SW620
PC-14
PC-14
GA-10
GA-10
LOXIMVI
LOXIMVI
OV7
OV7
SNU-308
NOMO-1
Hs 294T
MOLM-6
L-363
Hs 940.T
RKO
NCI-H2228
CCK-81
Hs 888.T
TUHR14TKB
SNU-503
HEC1B
LU-65
SNU-46
GI-1
NCI-H929
ML-1
M059K
SJSA-1
KARPAS-422
TTTHYROID
BV-173
NCI-H1755
Calu-1
BT328
KM12
KLE
SNU-216
PSTS
KMS-26
COLO-668
A3-KAW
NCI-H524
P12-ICHIKAWA
MOLT-3
Daudi
LS-1034
RS4;11
EB1
SEM
KMS-12-BM
A673
SUP-M2
L-428
EoL-1-cell
DB
697
DEL
NCI-H1155
LS-123
MV-4-11
KMS-18
KMS-34
WSU-DLCL2
SW620
PC-14
GA-10
LOXIMVI
OV7
SNU-308: 13.97 (log10 µM)
Synonyms: SNU-308, SNU308
NOMO-1: 13.19 (log10 µM)
Synonyms: NOMO-1, NOMO1
Hs 294T: 12.36 (log10 µM)
Synonyms: Hs 294T, Hs_294T, HS294T
MOLM-6: 12.22 (log10 µM)
Synonyms: MOLM-6, MOLM6
L-363: 12.22 (log10 µM)
Synonyms: L-363, L363
Hs 940.T: 11.90 (log10 µM)
Synonyms: Hs 940.T, Hs_940.T, Hs-940-T, Hs940-T, HS940T
RKO: 11.63 (log10 µM)
Synonyms: RKO
NCI-H2228: 9.50 (log10 µM)
Synonyms: NCI-H2228, NCIH2228
CCK-81: 9.41 (log10 µM)
Synonyms: CCK-81, CCK81
Hs 888.T: 9.16 (log10 µM)
Synonyms: Hs 888.T, Hs_888.T, HS888T
TUHR14TKB: 9.11 (log10 µM)
Synonyms: TUHR14TKB
SNU-503: 8.82 (log10 µM)
Synonyms: SNU-503, SNU503
HEC1B: 8.40 (log10 µM)
Synonyms: HEC1B
LU-65: 7.31 (log10 µM)
Synonyms: LU-65, LU65
SNU-46: 6.98 (log10 µM)
Synonyms: SNU-46, SNU46
GI-1: 6.19 (log10 µM)
Synonyms: GI-1, GI1
NCI-H929: 6.17 (log10 µM)
Synonyms: NCI-H929, NCIH929
ML-1: 5.19 (log10 µM)
Synonyms: ML-1, ML1
M059K: 4.99 (log10 µM)
Synonyms: M059K
SJSA-1: 4.92 (log10 µM)
Synonyms: SJSA-1, SJSA1
KARPAS-422: 4.68 (log10 µM)
Synonyms: KARPAS-422, KARPAS422
TTTHYROID: 4.50 (log10 µM)
Synonyms: TTTHYROID
BV-173: 4.49 (log10 µM)
Synonyms: BV-173, BV173
NCI-H1755: 4.38 (log10 µM)
Synonyms: NCI-H1755, NCIH1755
Calu-1: 4.35 (log10 µM)
Synonyms: Calu-1, CALU1
BT328: 4.27 (log10 µM)
Synonyms: BT328
KM12: 4.24 (log10 µM)
Synonyms: KM12, KM-12
KLE: 4.07 (log10 µM)
Synonyms: KLE
SNU-216: 4.00 (log10 µM)
Synonyms: SNU-216, SNU216
PSTS: 3.81 (log10 µM)
Synonyms: PSTS
: 0.00 (log10 µM)
Synonyms:
: 0.00 (log10 µM)
Synonyms:
: 0.00 (log10 µM)
Synonyms:
: 0.00 (log10 µM)
Synonyms:
: 0.00 (log10 µM)
Synonyms:
KMS-26: 1.39 (log10 µM)
Synonyms: KMS-26, KMS26
COLO-668: 1.37 (log10 µM)
Synonyms: COLO-668, COLO 668, COLO_668, COLO668
A3-KAW: 1.37 (log10 µM)
Synonyms: A3-KAW, A3/KAW, A3_KAW, A3KAW
NCI-H524: 1.37 (log10 µM)
Synonyms: NCI-H524, NCIH524
P12-ICHIKAWA: 1.36 (log10 µM)
Synonyms: P12-ICHIKAWA, P12ICHIKAWA
MOLT-3: 1.34 (log10 µM)
Synonyms: MOLT-3, MOLT3
Daudi: 1.31 (log10 µM)
Synonyms: Daudi, DAUDI
LS-1034: 1.27 (log10 µM)
Synonyms: LS-1034, LS1034
RS4;11: 1.27 (log10 µM)
Synonyms: RS4;11, RS4_11, RS4-11, RS411
EB1: 1.24 (log10 µM)
Synonyms: EB1
SEM: 1.22 (log10 µM)
Synonyms: SEM
KMS-12-BM: 1.21 (log10 µM)
Synonyms: KMS-12-BM, KMS12BM
A673: 1.19 (log10 µM)
Synonyms: A673, A-673
SUP-M2: 1.17 (log10 µM)
Synonyms: SUP-M2, SUPM2
L-428: 1.17 (log10 µM)
Synonyms: L-428, L428
EoL-1-cell: 1.14 (log10 µM)
Synonyms: EoL-1-cell, EOL-1, EOL1
DB: 1.11 (log10 µM)
Synonyms: DB
697: 1.10 (log10 µM)
Synonyms: 697
DEL: 1.08 (log10 µM)
Synonyms: DEL
NCI-H1155: 1.05 (log10 µM)
Synonyms: NCI-H1155, NCIH1155
LS-123: 1.04 (log10 µM)
Synonyms: LS-123, LS123
MV-4-11: 0.98 (log10 µM)
Synonyms: MV-4-11, MV411
KMS-18: 0.88 (log10 µM)
Synonyms: KMS-18, KMS18
KMS-34: 0.87 (log10 µM)
Synonyms: KMS-34, KMS34
WSU-DLCL2: 0.76 (log10 µM)
Synonyms: WSU-DLCL2, WSUDLCL2
SW620: 0.74 (log10 µM)
Synonyms: SW620, SW 620
PC-14: 0.74 (log10 µM)
Synonyms: PC-14, PC14
GA-10: 0.67 (log10 µM)
Synonyms: GA-10, GA10
LOXIMVI: 0.63 (log10 µM)
Synonyms: LOXIMVI, LOX IMVI, LOX_IMVI, LOX-IMVI
OV7: 0.59 (log10 µM)
Synonyms: OV7, OV-7
AAC
pIC50
* Plot represents the top and bottom 30 data points
** Error Bars represent the Median Absolute Deviation
Download SVG
Download Data as CSV
necrostatin-7: AAC
AAC
Tissues
0.00
0.05
0.10
0.15
0.20
0.25
0.30
0.35
thyroid
thyroid
cervix
cervix
prostate
prostate
salivary_gland
salivary_gland
central_nervous_system
central_nervous_system
kidney
kidney
skin
skin
bone
bone
liver
liver
pancreas
pancreas
breast
breast
endometrium
endometrium
upper_aerodigestive_tract
upper_aerodigestive_tract
ovary
ovary
urinary_tract
urinary_tract
soft_tissue
soft_tissue
oesophagus
oesophagus
unknown
unknown
biliary_tract
biliary_tract
stomach
stomach
pleura
pleura
autonomic_ganglia
autonomic_ganglia
lung
lung
large_intestine
large_intestine
haematopoietic_and_lymphoid_tissue
haematopoietic_and_lymphoid_tissue
0.00
1.00
2.00
3.00
4.00
5.00
6.00
7.00
salivary_gland
salivary_gland
cervix
cervix
haematopoietic_and_lymphoid_tissue
haematopoietic_and_lymphoid_tissue
ovary
ovary
liver
liver
oesophagus
oesophagus
soft_tissue
soft_tissue
large_intestine
large_intestine
pancreas
pancreas
lung
lung
breast
breast
stomach
stomach
skin
skin
urinary_tract
urinary_tract
bone
bone
autonomic_ganglia
autonomic_ganglia
upper_aerodigestive_tract
upper_aerodigestive_tract
prostate
prostate
central_nervous_system
central_nervous_system
endometrium
endometrium
kidney
kidney
unknown
unknown
thyroid
thyroid
pleura
pleura
biliary_tract
biliary_tract
AAC
pIC50
= Truncated outliers
Download SVG
Top molecular features associated with response to necrostatin-7
Feature Type
Gene
Dataset
Tissue
Stat
Standardized
Coefficient
Nominal ANOVA
p-value
mRNA
TMEM116
CTRPv2
pan-cancer
AAC
0.064
0.09
mRNA
DAPP1
CTRPv2
pan-cancer
AAC
0.069
0.09
mRNA
NELL2
CTRPv2
pan-cancer
AAC
0.067
0.09
mRNA
GNMT
CTRPv2
pan-cancer
AAC
0.07
0.09
mRNA
ALDH18A1
CTRPv2
pan-cancer
AAC
-0.068
0.09
mRNA
TADA2B
CTRPv2
pan-cancer
AAC
-0.064
0.09
mRNA
SLC2A5
CTRPv2
pan-cancer
AAC
0.067
0.09
mRNA
DNAJB8
CTRPv2
pan-cancer
AAC
0.07
0.09
mRNA
OSGEPL1
CTRPv2
pan-cancer
AAC
-0.064
0.09
mRNA
CYP3A43
CTRPv2
pan-cancer
AAC
0.063
0.09
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