About
Documentation
Cite Us!
Github
Download
News
Explore
Batch Query
Search
Site
Home
About
Documentation
PharmacoGx
Cite Us!
Tools
Explore
Batch Query
Search
GitHub
Datatypes
datasets
cell lines
tissues
drugs
genes
experiments
Home
/
Compounds
/
tigecycline
tigecycline
Synonyms
Sources
Names Used
CTRPv2
tigecycline
PharmacoGx
tigecycline
External IDs
Database
Identifier
Smiles:
CN(C)[C@H]1[C@@H]2C[C@@H]3Cc4c(cc(NC(=O)CNC(C)(C)C)c(O)c4C(=O)C3C(=O)[C@]2(O)C(=O)C(C(N)=O)C1=O)N(C)C
Pubchem:
54686904
FDA Approval Status
Approved
Plots
Cell Line Summary
Tissue Summary
Molecular Features
Number of cell lines tested with tigecycline
(per dataset)
0
50
100
150
200
250
300
350
400
# cell lines
CCLE
GDSC1000
gCSI
GRAY
FIMM
UHNBreast
CTRPv2
0
0
0
0
0
0
415
Download SVG
Number of tissues tested with tigecycline
(per dataset)
0
2
4
6
8
10
12
14
16
18
20
22
24
# tissues
CCLE
GDSC1000
gCSI
GRAY
FIMM
UHNBreast
CTRPv2
0
0
0
0
0
0
24
Download SVG
Dataset Select
all
CTRPv2
tigecycline: AAC
AAC
0.00
0.05
0.10
0.15
0.20
0.25
0.30
0.35
0.40
AM-38
AM-38
U-937
U-937
SU-DHL-6
SU-DHL-6
THP-1
THP-1
MM1-S
MM1-S
KMS-12-BM
KMS-12-BM
L-540
L-540
NU-DUL-1
NU-DUL-1
SNU-C5
SNU-C5
RCH-ACV
RCH-ACV
MOLT-16
MOLT-16
HEC-151
HEC-151
RS4;11
RS4;11
SW1573
SW1573
KMS-28BM
KMS-28BM
SU-DHL-8
SU-DHL-8
KMS-34
KMS-34
MONO-MAC-6
MONO-MAC-6
SU-DHL-4
SU-DHL-4
TUHR10TKB
TUHR10TKB
LoVo
LoVo
Sq-1
Sq-1
SUP-T11
SUP-T11
RI-1
RI-1
HPB-ALL
HPB-ALL
NCI-H2228
NCI-H2228
KMS-26
KMS-26
Hs 944.T
Hs 944.T
ECC10
ECC10
A2780
A2780
NCI-H2009
NCI-H2009
BHY
BHY
MKN45
MKN45
ONS-76
ONS-76
BFTC-909
BFTC-909
KMRC-20
KMRC-20
OUMS-23
OUMS-23
DLD-1
DLD-1
SK-CO-1
SK-CO-1
BEN
BEN
KU-19-19
KU-19-19
OVTOKO
OVTOKO
SNU-1066
SNU-1066
HCC1806
HCC1806
HPAF-II
HPAF-II
OVISE
OVISE
NUGC-4
NUGC-4
AGS
AGS
HEC-108
HEC-108
HMC-1-8
HMC-1-8
HT-29
HT-29
Ishikawa (Heraklio) 02 ER-
Ishikawa (Heraklio) 02 ER-
KYSE-180
KYSE-180
MOR/CPR
MOR/CPR
HEC-251
HEC-251
NCI-H292
NCI-H292
SNU-308
SNU-308
HCC1395
HCC1395
LN-18
LN-18
YD-15
YD-15
AM-38
U-937
SU-DHL-6
THP-1
MM1-S
KMS-12-BM
L-540
NU-DUL-1
SNU-C5
RCH-ACV
MOLT-16
HEC-151
RS4;11
SW1573
KMS-28BM
SU-DHL-8
KMS-34
MONO-MAC-6
SU-DHL-4
TUHR10TKB
LoVo
Sq-1
SUP-T11
RI-1
HPB-ALL
NCI-H2228
KMS-26
Hs 944.T
ECC10
A2780
NCI-H2009
BHY
MKN45
ONS-76
BFTC-909
KMRC-20
OUMS-23
DLD-1
SK-CO-1
BEN
KU-19-19
OVTOKO
SNU-1066
HCC1806
HPAF-II
OVISE
NUGC-4
AGS
HEC-108
HMC-1-8
HT-29
Ishikawa (Heraklio) 02 ER-
KYSE-180
MOR/CPR
HEC-251
NCI-H292
SNU-308
HCC1395
LN-18
YD-15
AM-38: 0.42
Synonyms: AM-38, AM38
U-937: 0.31
Synonyms: U-937, U937
SU-DHL-6: 0.29
Synonyms: SU-DHL-6, SUDHL6
THP-1: 0.28
Synonyms: THP-1, THP1
MM1-S: 0.28
Synonyms: MM1-S, MM1S, MM.1S
KMS-12-BM: 0.28
Synonyms: KMS-12-BM, KMS12BM
L-540: 0.27
Synonyms: L-540, L540
NU-DUL-1: 0.27
Synonyms: NU-DUL-1, NUDUL1
SNU-C5: 0.26
Synonyms: SNU-C5, SNUC5
RCH-ACV: 0.26
Synonyms: RCH-ACV, RCHACV
MOLT-16: 0.26
Synonyms: MOLT-16, MOLT16
HEC-151: 0.25
Synonyms: HEC-151, HEC151
RS4;11: 0.25
Synonyms: RS4;11, RS4_11, RS4-11, RS411
SW1573: 0.24
Synonyms: SW1573, SW 1573, SW_1573
KMS-28BM: 0.24
Synonyms: KMS-28BM, KMS28BM
SU-DHL-8: 0.23
Synonyms: SU-DHL-8, SUDHL8
KMS-34: 0.23
Synonyms: KMS-34, KMS34
MONO-MAC-6: 0.23
Synonyms: MONO-MAC-6, MONOMAC6
SU-DHL-4: 0.23
Synonyms: SU-DHL-4, SUDHL4
TUHR10TKB: 0.22
Synonyms: TUHR10TKB
LoVo: 0.22
Synonyms: LoVo, LOVO
Sq-1: 0.21
Synonyms: Sq-1, SQ1
SUP-T11: 0.21
Synonyms: SUP-T11, SUPT11
RI-1: 0.21
Synonyms: RI-1, RI1
HPB-ALL: 0.20
Synonyms: HPB-ALL, HPBALL
NCI-H2228: 0.20
Synonyms: NCI-H2228, NCIH2228
KMS-26: 0.20
Synonyms: KMS-26, KMS26
Hs 944.T: 0.20
Synonyms: Hs 944.T, Hs_944.T, Hs-944-T, HS944T
ECC10: 0.20
Synonyms: ECC10
A2780: 0.20
Synonyms: A2780
: 0.00
Synonyms:
: 0.00
Synonyms:
: 0.00
Synonyms:
: 0.00
Synonyms:
: 0.00
Synonyms:
NCI-H2009: 0.00
Synonyms: NCI-H2009, NCIH2009
BHY: 0.00
Synonyms: BHY
MKN45: 0.00
Synonyms: MKN45, MKN-45
ONS-76: 0.00
Synonyms: ONS-76, ONS76
BFTC-909: 0.00
Synonyms: BFTC-909, BFTC909
KMRC-20: 0.00
Synonyms: KMRC-20, KMRC20
OUMS-23: 0.00
Synonyms: OUMS-23, OUMS23
DLD-1: 0.00
Synonyms: DLD-1, DLD1
SK-CO-1: 0.00
Synonyms: SK-CO-1, SKCO1
BEN: 0.00
Synonyms: BEN
KU-19-19: 0.00
Synonyms: KU-19-19, KU1919
OVTOKO: 0.00
Synonyms: OVTOKO
SNU-1066: 0.00
Synonyms: SNU-1066, SNU1066
HCC1806: 0.00
Synonyms: HCC1806, hcc1806
HPAF-II: 0.00
Synonyms: HPAF-II, HPAFII
OVISE: 0.00
Synonyms: OVISE
NUGC-4: 0.00
Synonyms: NUGC-4, NUGC4
AGS: 0.00
Synonyms: AGS
HEC-108: 0.00
Synonyms: HEC-108, HEC108
HMC-1-8: 0.00
Synonyms: HMC-1-8, HMC18
HT-29: 0.00
Synonyms: HT-29, HT29
Ishikawa (Heraklio) 02 ER-: 0.00
Synonyms: Ishikawa (Heraklio) 02 ER-, Ishikawa__Heraklio__02_ER-, Ishikawa_Heraklio_02ER-, ISHIKAWAHERAKLIO02ER
KYSE-180: 0.00
Synonyms: KYSE-180, KYSE180
MOR/CPR: 0.00
Synonyms: MOR/CPR, MOR_CPR, MORCPR
HEC-251: 0.00
Synonyms: HEC-251, HEC251
NCI-H292: 0.00
Synonyms: NCI-H292, H292
SNU-308: 0.00
Synonyms: SNU-308, SNU308
HCC1395: 0.00
Synonyms: HCC1395, hcc1395
LN-18: 0.00
Synonyms: LN-18, LN18
YD-15: 0.00
Synonyms: YD-15, YD15
Download SVG
0.00
1.00
2.00
3.00
4.00
5.00
6.00
7.00
8.00
9.00
10.00
SW1710
SW1710
MEL-HO
MEL-HO
HCC1937
HCC1937
KCL-22
KCL-22
KMM-1
KMM-1
ES-2
ES-2
SNU-119
SNU-119
JURKAT
JURKAT
Panc 05.04
Panc 05.04
HEC-59
HEC-59
IPC-298
IPC-298
HCC-2108
HCC-2108
GAMG
GAMG
SNU-46
SNU-46
P31-FUJ
P31-FUJ
JHUEM-2
JHUEM-2
EBC-1
EBC-1
HUH-6-clone5
HUH-6-clone5
Caov-3
Caov-3
Hs 852.T
Hs 852.T
COLO-680N
COLO-680N
LS-123
LS-123
NCI-H2085
NCI-H2085
SNU-840
SNU-840
MV-4-11
MV-4-11
KM-H2
KM-H2
DOV13
DOV13
YD-38
YD-38
HT-115
HT-115
HCC-366
HCC-366
AMO-1
AMO-1
MM1-S
MM1-S
KMS-34
KMS-34
TUHR10TKB
TUHR10TKB
MHH-CALL-4
MHH-CALL-4
REC-1
REC-1
KP-N-S19s
KP-N-S19s
A2780
A2780
MONO-MAC-6
MONO-MAC-6
SUP-T1
SUP-T1
CCK-81
CCK-81
MOLT-16
MOLT-16
GDM-1
GDM-1
SUP-T11
SUP-T11
HPB-ALL
HPB-ALL
MC116
MC116
NB4
NB4
U-937
U-937
RCH-ACV
RCH-ACV
KARPAS-299
KARPAS-299
OCI-AML2
OCI-AML2
L-540
L-540
NU-DUL-1
NU-DUL-1
THP-1
THP-1
ECC10
ECC10
SU-DHL-6
SU-DHL-6
SU-DHL-8
SU-DHL-8
SU-DHL-4
SU-DHL-4
RS4;11
RS4;11
KMS-12-BM
KMS-12-BM
SW1710
MEL-HO
HCC1937
KCL-22
KMM-1
ES-2
SNU-119
JURKAT
Panc 05.04
HEC-59
IPC-298
HCC-2108
GAMG
SNU-46
P31-FUJ
JHUEM-2
EBC-1
HUH-6-clone5
Caov-3
Hs 852.T
COLO-680N
LS-123
NCI-H2085
SNU-840
MV-4-11
KM-H2
DOV13
YD-38
HT-115
HCC-366
AMO-1
MM1-S
KMS-34
TUHR10TKB
MHH-CALL-4
REC-1
KP-N-S19s
A2780
MONO-MAC-6
SUP-T1
CCK-81
MOLT-16
GDM-1
SUP-T11
HPB-ALL
MC116
NB4
U-937
RCH-ACV
KARPAS-299
OCI-AML2
L-540
NU-DUL-1
THP-1
ECC10
SU-DHL-6
SU-DHL-8
SU-DHL-4
RS4;11
KMS-12-BM
SW1710: 10.59 (log10 µM)
Synonyms: SW1710, SW-1710
MEL-HO: 4.88 (log10 µM)
Synonyms: MEL-HO, MELHO
HCC1937: 4.23 (log10 µM)
Synonyms: HCC1937, hcc1937
KCL-22: 4.14 (log10 µM)
Synonyms: KCL-22, KCL22
KMM-1: 3.99 (log10 µM)
Synonyms: KMM-1, KMM1
ES-2: 3.84 (log10 µM)
Synonyms: ES-2, ES2
SNU-119: 3.77 (log10 µM)
Synonyms: SNU-119, SNU119
JURKAT: 3.74 (log10 µM)
Synonyms: JURKAT, Jurkat
Panc 05.04: 3.64 (log10 µM)
Synonyms: Panc 05.04, Panc_05.04, PANC0504
HEC-59: 3.62 (log10 µM)
Synonyms: HEC-59, HEC59
IPC-298: 3.49 (log10 µM)
Synonyms: IPC-298, IPC298
HCC-2108: 3.04 (log10 µM)
Synonyms: HCC-2108, HCC2108
GAMG: 3.03 (log10 µM)
Synonyms: GAMG
SNU-46: 3.02 (log10 µM)
Synonyms: SNU-46, SNU46
P31-FUJ: 2.79 (log10 µM)
Synonyms: P31-FUJ, P31/FUJ, P31_FUJ, P31FUJ
JHUEM-2: 2.70 (log10 µM)
Synonyms: JHUEM-2, JHUEM2
EBC-1: 2.69 (log10 µM)
Synonyms: EBC-1, EBC1
HUH-6-clone5: 2.67 (log10 µM)
Synonyms: HUH-6-clone5, HuH-6, HUH6
Caov-3: 2.66 (log10 µM)
Synonyms: Caov-3, CAOV3
Hs 852.T: 2.56 (log10 µM)
Synonyms: Hs 852.T, Hs_852.T, HS852T
COLO-680N: 2.53 (log10 µM)
Synonyms: COLO-680N, COLO 680N, COLO680N
LS-123: 2.49 (log10 µM)
Synonyms: LS-123, LS123
NCI-H2085: 2.47 (log10 µM)
Synonyms: NCI-H2085, NCIH2085
SNU-840: 2.46 (log10 µM)
Synonyms: SNU-840, SNU840
MV-4-11: 2.45 (log10 µM)
Synonyms: MV-4-11, MV411
KM-H2: 2.44 (log10 µM)
Synonyms: KM-H2, KMH2
DOV13: 2.40 (log10 µM)
Synonyms: DOV13
YD-38: 2.35 (log10 µM)
Synonyms: YD-38, YD38
HT-115: 2.34 (log10 µM)
Synonyms: HT-115, HT115
HCC-366: 2.34 (log10 µM)
Synonyms: HCC-366, HCC366
: 0.00 (log10 µM)
Synonyms:
: 0.00 (log10 µM)
Synonyms:
: 0.00 (log10 µM)
Synonyms:
: 0.00 (log10 µM)
Synonyms:
: 0.00 (log10 µM)
Synonyms:
AMO-1: 0.71 (log10 µM)
Synonyms: AMO-1, AMO1
MM1-S: 0.71 (log10 µM)
Synonyms: MM1-S, MM1S, MM.1S
KMS-34: 0.69 (log10 µM)
Synonyms: KMS-34, KMS34
TUHR10TKB: 0.69 (log10 µM)
Synonyms: TUHR10TKB
MHH-CALL-4: 0.66 (log10 µM)
Synonyms: MHH-CALL-4, MHHCALL4
REC-1: 0.65 (log10 µM)
Synonyms: REC-1, REC1
KP-N-S19s: 0.65 (log10 µM)
Synonyms: KP-N-S19s, KP-N-SI9s, KPNSI9S
A2780: 0.63 (log10 µM)
Synonyms: A2780
MONO-MAC-6: 0.62 (log10 µM)
Synonyms: MONO-MAC-6, MONOMAC6
SUP-T1: 0.58 (log10 µM)
Synonyms: SUP-T1, SUPT1
CCK-81: 0.57 (log10 µM)
Synonyms: CCK-81, CCK81
MOLT-16: 0.56 (log10 µM)
Synonyms: MOLT-16, MOLT16
GDM-1: 0.55 (log10 µM)
Synonyms: GDM-1, GDM1
SUP-T11: 0.53 (log10 µM)
Synonyms: SUP-T11, SUPT11
HPB-ALL: 0.52 (log10 µM)
Synonyms: HPB-ALL, HPBALL
MC116: 0.50 (log10 µM)
Synonyms: MC116
NB4: 0.47 (log10 µM)
Synonyms: NB4, NB-4
U-937: 0.46 (log10 µM)
Synonyms: U-937, U937
RCH-ACV: 0.46 (log10 µM)
Synonyms: RCH-ACV, RCHACV
KARPAS-299: 0.44 (log10 µM)
Synonyms: KARPAS-299, KARPAS299
OCI-AML2: 0.44 (log10 µM)
Synonyms: OCI-AML2, OCIAML2
L-540: 0.41 (log10 µM)
Synonyms: L-540, L540
NU-DUL-1: 0.41 (log10 µM)
Synonyms: NU-DUL-1, NUDUL1
THP-1: 0.40 (log10 µM)
Synonyms: THP-1, THP1
ECC10: 0.39 (log10 µM)
Synonyms: ECC10
SU-DHL-6: 0.38 (log10 µM)
Synonyms: SU-DHL-6, SUDHL6
SU-DHL-8: 0.37 (log10 µM)
Synonyms: SU-DHL-8, SUDHL8
SU-DHL-4: 0.32 (log10 µM)
Synonyms: SU-DHL-4, SUDHL4
RS4;11: 0.30 (log10 µM)
Synonyms: RS4;11, RS4_11, RS4-11, RS411
KMS-12-BM: 0.23 (log10 µM)
Synonyms: KMS-12-BM, KMS12BM
AAC
pIC50
* Plot represents the top and bottom 30 data points
** Error Bars represent the Median Absolute Deviation
Download SVG
Download Data as CSV
tigecycline: AAC
AAC
Tissues
0.00
0.05
0.10
0.15
0.20
0.25
0.30
0.35
0.40
salivary_gland
salivary_gland
upper_aerodigestive_tract
upper_aerodigestive_tract
stomach
stomach
prostate
prostate
thyroid
thyroid
biliary_tract
biliary_tract
bone
bone
central_nervous_system
central_nervous_system
urinary_tract
urinary_tract
endometrium
endometrium
kidney
kidney
oesophagus
oesophagus
breast
breast
lung
lung
pleura
pleura
pancreas
pancreas
cervix
cervix
ovary
ovary
large_intestine
large_intestine
soft_tissue
soft_tissue
liver
liver
skin
skin
autonomic_ganglia
autonomic_ganglia
haematopoietic_and_lymphoid_tissue
haematopoietic_and_lymphoid_tissue
0.00
0.50
1.00
1.50
2.00
2.50
3.00
3.50
4.00
4.50
prostate
prostate
salivary_gland
salivary_gland
cervix
cervix
haematopoietic_and_lymphoid_tissue
haematopoietic_and_lymphoid_tissue
lung
lung
autonomic_ganglia
autonomic_ganglia
soft_tissue
soft_tissue
endometrium
endometrium
skin
skin
pleura
pleura
thyroid
thyroid
bone
bone
biliary_tract
biliary_tract
urinary_tract
urinary_tract
oesophagus
oesophagus
breast
breast
stomach
stomach
central_nervous_system
central_nervous_system
pancreas
pancreas
large_intestine
large_intestine
liver
liver
ovary
ovary
upper_aerodigestive_tract
upper_aerodigestive_tract
kidney
kidney
AAC
pIC50
= Truncated outliers
Download SVG
Top molecular features associated with response to tigecycline
Feature Type
Gene
Dataset
Tissue
Stat
Standardized
Coefficient
Nominal ANOVA
p-value
mRNA
ZNF714
CTRPv2
pan-cancer
AAC
0.14
0.005
mRNA
UBAP2
CTRPv2
pan-cancer
AAC
0.14
0.005
mRNA
EPDR1
CTRPv2
pan-cancer
AAC
-0.16
0.005
mRNA
NSMF
CTRPv2
pan-cancer
AAC
0.14
0.005
mRNA
NDUFB10
CTRPv2
pan-cancer
AAC
0.14
0.005
mRNA
NUP210
CTRPv2
pan-cancer
AAC
0.18
0.005
mRNA
PELI3
CTRPv2
pan-cancer
AAC
0.14
0.005
mRNA
RAD51
CTRPv2
pan-cancer
AAC
0.15
0.005
mRNA
TIMM21
CTRPv2
pan-cancer
AAC
0.14
0.005
mRNA
KMT2C
CTRPv2
pan-cancer
AAC
0.14
0.005
← Previous
1
2
…
36
37
38
…
199
200
Next →
Download CSV