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SB-525334

SB-525334

Synonyms

Sources	Names Used
CTRPv2	SB-525334
PharmacoGx	SB-525334

External IDs

Database	Identifier
Smiles:	Cc1cccc(n1)-c1[nH]c(nc1-c1ccc2nccnc2c1)C(C)(C)C
Pubchem:	9967941

Annotated Targets

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to SB-525334

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	CIC	CTRPv2	pan-cancer	AAC	0.22	7e-09
mRNA	ARC	CTRPv2	pan-cancer	AAC	0.24	8e-09
mRNA	CBX2	CTRPv2	pan-cancer	AAC	0.24	8e-09
mRNA	HERC4	CTRPv2	pan-cancer	AAC	-0.22	9e-09
mRNA	FAM234B	CTRPv2	pan-cancer	AAC	0.21	9e-09
mRNA	OLFM1	CTRPv2	pan-cancer	AAC	0.23	9e-09
mRNA	PLIN3	CTRPv2	pan-cancer	AAC	-0.22	1e-08
mRNA	ATP2B3	CTRPv2	pan-cancer	AAC	0.22	1e-08
mRNA	MAPK8IP2	CTRPv2	pan-cancer	AAC	0.23	1e-08
mRNA	GPRIN1	CTRPv2	pan-cancer	AAC	0.22	1e-08

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