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SB-525334

SB-525334

Synonyms

Sources	Names Used
CTRPv2	SB-525334
PharmacoGx	SB-525334

External IDs

Database	Identifier
Smiles:	Cc1cccc(n1)-c1[nH]c(nc1-c1ccc2nccnc2c1)C(C)(C)C
Pubchem:	9967941

Annotated Targets

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to SB-525334

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	AAED1	CTRPv2	pan-cancer	AAC	-0.15	0.0003
mRNA	AATK	CTRPv2	pan-cancer	AAC	0.14	0.0003
mRNA	AATK-AS1	CTRPv2	pan-cancer	AAC	0.21	2e-07
mRNA	ABAT	CTRPv2	pan-cancer	AAC	0.16	2e-05
mRNA	ABCA3	CTRPv2	pan-cancer	AAC	0.14	0.0003
mRNA	ABCA5	CTRPv2	pan-cancer	AAC	0.13	0.0004
mRNA	ABCB6	CTRPv2	pan-cancer	AAC	0.13	0.001
mRNA	ABCC8	CTRPv2	pan-cancer	AAC	0.15	4e-05
mRNA	ABHD14A	CTRPv2	pan-cancer	AAC	0.13	0.001
mRNA	ABI3BP	CTRPv2	pan-cancer	AAC	-0.13	0.0007

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