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ruxolitinib

Synonyms

SourcesNames Used
GDSC1000Ruxolitinib
CTRPv2ruxolitinib
PharmacoGx ruxolitinib

External IDs

DatabaseIdentifier
Smiles: N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
Pubchem: 25126798

Annotated Targets

JAK2, JAK1, JAK3, TYK2

FDA Approval Status

Approved
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Top molecular features associated with response to ruxolitinib


Feature TypeStandardized
Nominal ANOVA
mRNA HBG2 GDSC1000 pan-cancer AAC 0.24 3e-14
mRNA PSTPIP2 CTRPv2 pan-cancer AAC 0.26 4e-14
mRNA RBPMS2 CTRPv2 pan-cancer AAC 0.26 4e-14
mRNA GYPB CTRPv2 pan-cancer AAC 0.25 7e-14
mRNA AMHR2 GDSC1000 pan-cancer AAC 0.24 7e-14
mRNA OR2H2 CTRPv2 pan-cancer AAC 0.25 7e-14
mRNA NFE2 CTRPv2 pan-cancer AAC 0.26 7e-14
mRNA KLF1 GDSC1000 pan-cancer AAC 0.24 8e-14
mRNA P2RY1 CTRPv2 pan-cancer AAC 0.25 9e-14
mRNA CISH GDSC1000 pan-cancer AAC 0.26 1e-13
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