1. Home/
  2. Compounds/
  3. ruxolitinib

ruxolitinib

Synonyms

SourcesNames Used
GDSC1000Ruxolitinib
CTRPv2ruxolitinib
PharmacoGx ruxolitinib

External IDs

DatabaseIdentifier
Smiles: N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
Pubchem: 25126798

Annotated Targets

JAK2, JAK1, JAK3, TYK2

FDA Approval Status

Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to ruxolitinib


Feature TypeStandardized
Nominal ANOVA
mRNA GP6 CTRPv2 pan-cancer AAC 0.27 6e-16
mRNA HBD CTRPv2 pan-cancer AAC 0.27 6e-16
mRNA CD33 CTRPv2 pan-cancer AAC 0.29 7e-16
mRNA GPR85 CTRPv2 pan-cancer AAC 0.27 1e-15
mRNA VASP CTRPv2 pan-cancer AAC 0.27 1e-15
mRNA USP15 CTRPv2 pan-cancer AAC 0.27 2e-15
mRNA IL23R GDSC1000 pan-cancer AAC 0.26 2e-15
mRNA HYAL3 CTRPv2 pan-cancer AAC 0.27 2e-15
mRNA PLVAP CTRPv2 pan-cancer AAC 0.27 2e-15
mRNA MFSD2B CTRPv2 pan-cancer AAC 0.26 3e-15
Download CSV