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ruxolitinib

Synonyms

SourcesNames Used
GDSC1000Ruxolitinib
CTRPv2ruxolitinib
PharmacoGx ruxolitinib

External IDs

DatabaseIdentifier
Smiles: N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
Pubchem: 25126798

Annotated Targets

JAK2, JAK1, JAK3, TYK2

FDA Approval Status

Approved
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Top molecular features associated with response to ruxolitinib


Feature TypeStandardized
Nominal ANOVA
mRNA ATM GDSC1000 pan-cancer AAC -0.17 7e-06
mRNA SLC23A1 CTRPv2 pan-cancer AAC -0.16 7e-06
mRNA OTP CTRPv2 pan-cancer AAC 0.15 7e-06
mRNA PHGDH GDSC1000 pan-cancer AAC -0.15 7e-06
mRNA MYLK4 CTRPv2 pan-cancer AAC 0.15 7e-06
mRNA PPP2R2D CTRPv2 pan-cancer AAC 0.15 7e-06
mRNA ACSBG1 CTRPv2 pan-cancer AAC 0.15 7e-06
mRNA C2orf88 CTRPv2 pan-cancer AAC 0.15 8e-06
mRNA EVI2B GDSC1000 pan-cancer AAC -0.21 8e-06
mRNA ACVR1 GDSC1000 pan-cancer AAC 0.17 8e-06
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