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ruxolitinib

Synonyms

SourcesNames Used
GDSC1000Ruxolitinib
CTRPv2ruxolitinib
PharmacoGx ruxolitinib

External IDs

DatabaseIdentifier
Smiles: N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
Pubchem: 25126798

Annotated Targets

JAK2, JAK1, JAK3, TYK2

FDA Approval Status

Approved
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Top molecular features associated with response to ruxolitinib


Feature TypeStandardized
Nominal ANOVA
mRNA POU1F1 GDSC1000 pan-cancer AAC 0.14 6e-06
mRNA ABCD2 GDSC1000 pan-cancer AAC 0.16 6e-06
mRNA GFI1B CTRPv2 pan-cancer AAC 0.15 7e-06
mRNA IL18RAP CTRPv2 pan-cancer AAC 0.15 7e-06
mRNA ELOVL6 CTRPv2 pan-cancer AAC 0.15 7e-06
mRNA RNF24 CTRPv2 pan-cancer AAC 0.16 7e-06
mRNA CA1 CTRPv2 pan-cancer AAC 0.15 7e-06
mRNA SPTA1 GDSC1000 pan-cancer AAC 0.15 7e-06
mRNA GBP4 CTRPv2 pan-cancer AAC 0.16 7e-06
mRNA FOXP3 CTRPv2 pan-cancer AAC 0.15 7e-06
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