1. Home/
  2. Compounds/
  3. ruxolitinib

ruxolitinib

Synonyms

SourcesNames Used
GDSC1000Ruxolitinib
CTRPv2ruxolitinib
PharmacoGx ruxolitinib

External IDs

DatabaseIdentifier
Smiles: N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
Pubchem: 25126798

Annotated Targets

JAK2, JAK1, JAK3, TYK2

FDA Approval Status

Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to ruxolitinib


Feature TypeStandardized
Nominal ANOVA
mRNA SMIM10 CTRPv2 pan-cancer AAC 0.29 4e-17
mRNA ASIC4 CTRPv2 pan-cancer AAC 0.28 4e-17
mRNA RASGRP4 CTRPv2 pan-cancer AAC 0.29 6e-17
mRNA EXOC3L2 CTRPv2 pan-cancer AAC 0.28 7e-17
mRNA CA1 GDSC1000 pan-cancer AAC 0.27 7e-17
mRNA CR1L CTRPv2 pan-cancer AAC 0.28 9e-17
mRNA TAL1 CTRPv2 pan-cancer AAC 0.28 2e-16
mRNA SPN CTRPv2 pan-cancer AAC 0.37 3e-16
mRNA PDZD8 CTRPv2 pan-cancer AAC 0.28 3e-16
mRNA CRYBB2 CTRPv2 pan-cancer AAC 0.27 5e-16
Download CSV