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ruxolitinib

Synonyms

SourcesNames Used
GDSC1000Ruxolitinib
CTRPv2ruxolitinib
PharmacoGx ruxolitinib

External IDs

DatabaseIdentifier
Smiles: N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
Pubchem: 25126798

Annotated Targets

JAK2, JAK1, JAK3, TYK2

FDA Approval Status

Approved
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Top molecular features associated with response to ruxolitinib


Feature TypeStandardized
Nominal ANOVA
mRNA GBP5 GDSC1000 pan-cancer AAC 0.16 4e-06
mRNA PDE6G CTRPv2 pan-cancer AAC 0.16 4e-06
mRNA SSH2 CTRPv2 pan-cancer AAC -0.17 4e-06
mRNA FES CTRPv2 pan-cancer AAC 0.17 4e-06
mRNA ZNRF1 GDSC1000 pan-cancer AAC 0.16 4e-06
mRNA OOEP GDSC1000 pan-cancer AAC 0.15 4e-06
mRNA ADAMTS14 CTRPv2 pan-cancer AAC 0.15 4e-06
mRNA CFP CTRPv2 pan-cancer AAC 0.16 4e-06
mRNA FCRLA CTRPv2 pan-cancer AAC -0.17 4e-06
mRNA FAM65B GDSC1000 pan-cancer AAC -0.18 4e-06
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