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ruxolitinib

Synonyms

SourcesNames Used
GDSC1000Ruxolitinib
CTRPv2ruxolitinib
PharmacoGx ruxolitinib

External IDs

DatabaseIdentifier
Smiles: N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
Pubchem: 25126798

Annotated Targets

JAK2, JAK1, JAK3, TYK2

FDA Approval Status

Approved
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Top molecular features associated with response to ruxolitinib


Feature TypeStandardized
Nominal ANOVA
mRNA NUDT19 CTRPv2 pan-cancer AAC 0.17 2e-06
mRNA ST3GAL2 CTRPv2 pan-cancer AAC 0.17 2e-06
mRNA SELP GDSC1000 pan-cancer AAC 0.15 2e-06
mRNA CD180 GDSC1000 pan-cancer AAC -0.18 2e-06
mRNA PKHD1L1 GDSC1000 pan-cancer AAC -0.17 2e-06
mRNA RNF130 CTRPv2 pan-cancer AAC 0.16 2e-06
mRNA RGS9BP CTRPv2 pan-cancer AAC 0.16 2e-06
mRNA CYP19A1 GDSC1000 pan-cancer AAC 0.17 2e-06
mRNA IRX1 CTRPv2 pan-cancer AAC 0.16 2e-06
mRNA KIAA0930 GDSC1000 pan-cancer AAC -0.16 2e-06
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