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ruxolitinib

Synonyms

SourcesNames Used
GDSC1000Ruxolitinib
CTRPv2ruxolitinib
PharmacoGx ruxolitinib

External IDs

DatabaseIdentifier
Smiles: N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
Pubchem: 25126798

Annotated Targets

JAK2, JAK1, JAK3, TYK2

FDA Approval Status

Approved
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Top molecular features associated with response to ruxolitinib


Feature TypeStandardized
Nominal ANOVA
mRNA SEMA4A GDSC1000 pan-cancer AAC -0.19 2e-06
mRNA CXCR4 CTRPv2 pan-cancer AAC -0.19 2e-06
mRNA GATAD1 CTRPv2 pan-cancer AAC 0.16 2e-06
mRNA ADAM18 GDSC1000 pan-cancer AAC 0.15 2e-06
mRNA FCRL1 GDSC1000 pan-cancer AAC -0.17 2e-06
mRNA FAM129C GDSC1000 pan-cancer AAC -0.17 2e-06
mRNA CD19 CTRPv2 pan-cancer AAC -0.18 2e-06
mRNA TFEB CTRPv2 pan-cancer AAC -0.18 2e-06
mRNA ST6GAL1 GDSC1000 pan-cancer AAC -0.18 2e-06
mRNA MS4A3 CTRPv2 pan-cancer AAC 0.16 2e-06
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