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ruxolitinib

Synonyms

SourcesNames Used
GDSC1000Ruxolitinib
CTRPv2ruxolitinib
PharmacoGx ruxolitinib

External IDs

DatabaseIdentifier
Smiles: N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
Pubchem: 25126798

Annotated Targets

JAK2, JAK1, JAK3, TYK2

FDA Approval Status

Approved
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Top molecular features associated with response to ruxolitinib


Feature TypeStandardized
Nominal ANOVA
mRNA TRIM10 GDSC1000 pan-cancer AAC 0.16 1e-06
mRNA CECR5 GDSC1000 pan-cancer AAC -0.16 1e-06
mRNA TNFRSF13B GDSC1000 pan-cancer AAC -0.17 1e-06
mRNA ADAMTS14 GDSC1000 pan-cancer AAC 0.16 1e-06
mRNA UCMA CTRPv2 pan-cancer AAC 0.16 1e-06
mRNA PVRIG CTRPv2 pan-cancer AAC -0.17 1e-06
mRNA SLC27A2 CTRPv2 pan-cancer AAC 0.17 1e-06
mRNA OTUD5 GDSC1000 pan-cancer AAC 0.16 1e-06
mRNA KIAA1586 CTRPv2 pan-cancer AAC 0.18 1e-06
mRNA CCR4 CTRPv2 pan-cancer AAC 0.16 2e-06
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