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ruxolitinib

Synonyms

SourcesNames Used
GDSC1000Ruxolitinib
CTRPv2ruxolitinib
PharmacoGx ruxolitinib

External IDs

DatabaseIdentifier
Smiles: N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
Pubchem: 25126798

Annotated Targets

JAK2, JAK1, JAK3, TYK2

FDA Approval Status

Approved
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Top molecular features associated with response to ruxolitinib


Feature TypeStandardized
Nominal ANOVA
mRNA BIN2 CTRPv2 pan-cancer AAC 0.21 4e-07
mRNA GOLGA8R CTRPv2 pan-cancer AAC 0.18 4e-07
mRNA PECAM1 CTRPv2 pan-cancer AAC 0.17 4e-07
mRNA USP44 CTRPv2 pan-cancer AAC 0.17 4e-07
mRNA ZNF560 CTRPv2 pan-cancer AAC 0.17 4e-07
mRNA PIM2 GDSC1000 pan-cancer AAC 0.21 4e-07
mRNA TTC7B CTRPv2 pan-cancer AAC 0.18 5e-07
mRNA MS4A4A CTRPv2 pan-cancer AAC 0.17 5e-07
mRNA SGSM3 CTRPv2 pan-cancer AAC -0.18 5e-07
mRNA SIGLEC14 CTRPv2 pan-cancer AAC 0.17 5e-07
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