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ruxolitinib

Synonyms

SourcesNames Used
GDSC1000Ruxolitinib
CTRPv2ruxolitinib
PharmacoGx ruxolitinib

External IDs

DatabaseIdentifier
Smiles: N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
Pubchem: 25126798

Annotated Targets

JAK2, JAK1, JAK3, TYK2

FDA Approval Status

Approved
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Top molecular features associated with response to ruxolitinib


Feature TypeStandardized
Nominal ANOVA
mRNA C15orf53 CTRPv2 pan-cancer AAC 0.18 5e-08
mRNA TUBA3E GDSC1000 pan-cancer AAC 0.17 5e-08
mRNA HEPH GDSC1000 pan-cancer AAC 0.2 6e-08
mRNA CD22 CTRPv2 pan-cancer AAC -0.2 6e-08
mRNA ARV1 CTRPv2 pan-cancer AAC 0.19 6e-08
mRNA STAP1 GDSC1000 pan-cancer AAC -0.22 7e-08
mRNA PCYT1B CTRPv2 pan-cancer AAC 0.19 7e-08
mRNA CFAP161 CTRPv2 pan-cancer AAC 0.18 7e-08
mRNA IL27RA CTRPv2 pan-cancer AAC 0.19 7e-08
mRNA TMEM217 CTRPv2 pan-cancer AAC 0.18 8e-08
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