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ruxolitinib

Synonyms

SourcesNames Used
GDSC1000Ruxolitinib
CTRPv2ruxolitinib
PharmacoGx ruxolitinib

External IDs

DatabaseIdentifier
Smiles: N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
Pubchem: 25126798

Annotated Targets

JAK2, JAK1, JAK3, TYK2

FDA Approval Status

Approved
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Top molecular features associated with response to ruxolitinib


Feature TypeStandardized
Nominal ANOVA
mRNA TLR10 GDSC1000 pan-cancer AAC -0.21 2e-08
mRNA TUBB1 GDSC1000 pan-cancer AAC 0.18 2e-08
mRNA LDB1 GDSC1000 pan-cancer AAC 0.2 2e-08
mRNA GP1BA GDSC1000 pan-cancer AAC 0.18 2e-08
mRNA ERMAP CTRPv2 pan-cancer AAC 0.19 2e-08
mRNA PIWIL3 CTRPv2 pan-cancer AAC 0.19 2e-08
mRNA PAWR GDSC1000 pan-cancer AAC -0.22 2e-08
mRNA NMI CTRPv2 pan-cancer AAC 0.22 2e-08
mRNA ARRB1 CTRPv2 pan-cancer AAC 0.19 2e-08
mRNA UNC13D CTRPv2 pan-cancer AAC 0.2 2e-08
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