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ruxolitinib

Synonyms

SourcesNames Used
GDSC1000Ruxolitinib
CTRPv2ruxolitinib
PharmacoGx ruxolitinib

External IDs

DatabaseIdentifier
Smiles: N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
Pubchem: 25126798

Annotated Targets

JAK2, JAK1, JAK3, TYK2

FDA Approval Status

Approved
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Top molecular features associated with response to ruxolitinib


Feature TypeStandardized
Nominal ANOVA
mRNA ZNRF4 CTRPv2 pan-cancer AAC 0.19 6e-09
mRNA AK3 CTRPv2 pan-cancer AAC 0.2 6e-09
mRNA NSMAF CTRPv2 pan-cancer AAC 0.21 6e-09
mRNA SAMD3 GDSC1000 pan-cancer AAC 0.19 6e-09
mRNA FCGR2A CTRPv2 pan-cancer AAC 0.21 7e-09
mRNA DYRK1A CTRPv2 pan-cancer AAC 0.2 7e-09
mRNA GFI1B GDSC1000 pan-cancer AAC 0.19 7e-09
mRNA LINC00694 CTRPv2 pan-cancer AAC 0.2 7e-09
mRNA CD79A GDSC1000 pan-cancer AAC -0.23 7e-09
mRNA ANKRD55 CTRPv2 pan-cancer AAC 0.19 7e-09
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