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ruxolitinib

Synonyms

SourcesNames Used
GDSC1000Ruxolitinib
CTRPv2ruxolitinib
PharmacoGx ruxolitinib

External IDs

DatabaseIdentifier
Smiles: N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
Pubchem: 25126798

Annotated Targets

JAK2, JAK1, JAK3, TYK2

FDA Approval Status

Approved
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Top molecular features associated with response to ruxolitinib


Feature TypeStandardized
Nominal ANOVA
mRNA TNFSF9 GDSC1000 pan-cancer AAC -0.1 0.004
mRNA GPX4 GDSC1000 pan-cancer AAC -0.096 0.004
mRNA C1orf54 CTRPv2 pan-cancer AAC -0.1 0.004
mRNA ANP32A CTRPv2 pan-cancer AAC 0.11 0.004
mRNA SLC38A1 GDSC1000 pan-cancer AAC -0.1 0.004
mRNA ST3GAL6 GDSC1000 pan-cancer AAC -0.11 0.004
mRNA ICOS GDSC1000 pan-cancer AAC 0.096 0.004
mRNA CFAP73 GDSC1000 pan-cancer AAC -0.099 0.004
mRNA GJC1 GDSC1000 pan-cancer AAC -0.11 0.004
mRNA GTF3C2 CTRPv2 pan-cancer AAC 0.11 0.004
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