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ruxolitinib

Synonyms

SourcesNames Used
GDSC1000Ruxolitinib
CTRPv2ruxolitinib
PharmacoGx ruxolitinib

External IDs

DatabaseIdentifier
Smiles: N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
Pubchem: 25126798

Annotated Targets

JAK2, JAK1, JAK3, TYK2

FDA Approval Status

Approved
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Top molecular features associated with response to ruxolitinib


Feature TypeStandardized
Nominal ANOVA
mRNA LYL1 CTRPv2 pan-cancer AAC 0.23 2e-09
mRNA ZNF792 CTRPv2 pan-cancer AAC 0.21 2e-09
mRNA SLC40A1 CTRPv2 pan-cancer AAC 0.21 2e-09
mRNA SHANK3 CTRPv2 pan-cancer AAC 0.2 2e-09
mRNA ZBTB16 CTRPv2 pan-cancer AAC 0.21 2e-09
mRNA RHD CTRPv2 pan-cancer AAC 0.2 2e-09
mRNA KCNH2 CTRPv2 pan-cancer AAC 0.21 2e-09
mRNA ASIC4 GDSC1000 pan-cancer AAC 0.2 2e-09
mRNA PIM1 CTRPv2 pan-cancer AAC 0.21 2e-09
mRNA FCRLA GDSC1000 pan-cancer AAC -0.24 3e-09
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