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ruxolitinib

Synonyms

SourcesNames Used
GDSC1000Ruxolitinib
CTRPv2ruxolitinib
PharmacoGx ruxolitinib

External IDs

DatabaseIdentifier
Smiles: N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
Pubchem: 25126798

Annotated Targets

JAK2, JAK1, JAK3, TYK2

FDA Approval Status

Approved
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Top molecular features associated with response to ruxolitinib


Feature TypeStandardized
Nominal ANOVA
mRNA COL6A5 GDSC1000 pan-cancer AAC 0.32 9e-24
mRNA CETP CTRPv2 pan-cancer AAC 0.33 2e-23
mRNA JAK2 CTRPv2 pan-cancer AAC 0.33 3e-23
mRNA FCER1A CTRPv2 pan-cancer AAC 0.32 1e-22
mRNA GP1BA CTRPv2 pan-cancer AAC 0.33 3e-22
mRNA C11orf21 CTRPv2 pan-cancer AAC 0.34 7e-22
mRNA GATA1 CTRPv2 pan-cancer AAC 0.32 1e-21
mRNA HPSE2 CTRPv2 pan-cancer AAC 0.32 1e-21
mRNA MINPP1 CTRPv2 pan-cancer AAC 0.31 4e-21
mRNA APOL4 CTRPv2 pan-cancer AAC 0.32 7e-21
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