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ruxolitinib

Synonyms

SourcesNames Used
GDSC1000Ruxolitinib
CTRPv2ruxolitinib
PharmacoGx ruxolitinib

External IDs

DatabaseIdentifier
Smiles: N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
Pubchem: 25126798

Annotated Targets

JAK2, JAK1, JAK3, TYK2

FDA Approval Status

Approved
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Top molecular features associated with response to ruxolitinib


Feature TypeStandardized
Nominal ANOVA
mRNA BMP10 CTRPv2 pan-cancer AAC 0.097 0.004
mRNA THUMPD2 CTRPv2 pan-cancer AAC 0.1 0.004
mRNA NOD2 CTRPv2 pan-cancer AAC 0.1 0.004
mRNA UBR4 CTRPv2 pan-cancer AAC 0.1 0.004
mRNA ZNF496 CTRPv2 pan-cancer AAC 0.1 0.004
mRNA GATAD2B CTRPv2 pan-cancer AAC -0.11 0.004
mRNA RNF144B CTRPv2 pan-cancer AAC -0.1 0.004
mRNA GPR68 CTRPv2 pan-cancer AAC 0.098 0.004
mRNA ABCB10 GDSC1000 pan-cancer AAC 0.11 0.004
mRNA TM6SF1 GDSC1000 pan-cancer AAC 0.1 0.004
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