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ruxolitinib

Synonyms

SourcesNames Used
GDSC1000Ruxolitinib
CTRPv2ruxolitinib
PharmacoGx ruxolitinib

External IDs

DatabaseIdentifier
Smiles: N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
Pubchem: 25126798

Annotated Targets

JAK2, JAK1, JAK3, TYK2

FDA Approval Status

Approved
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Top molecular features associated with response to ruxolitinib


Feature TypeStandardized
Nominal ANOVA
mRNA GIPC3 CTRPv2 pan-cancer AAC 0.1 0.004
mRNA CYP2U1 CTRPv2 pan-cancer AAC -0.11 0.004
mRNA TMEM246 GDSC1000 pan-cancer AAC 0.11 0.004
mRNA TYK2 CTRPv2 pan-cancer AAC 0.13 0.004
mRNA ZNF223 CTRPv2 pan-cancer AAC 0.11 0.004
mRNA ZPLD1 GDSC1000 pan-cancer AAC 0.093 0.004
mRNA RNF24 GDSC1000 pan-cancer AAC 0.098 0.004
mRNA STEAP3 CTRPv2 pan-cancer AAC 0.11 0.004
mRNA SLC4A9 CTRPv2 pan-cancer AAC -0.098 0.004
mRNA KATNAL2 CTRPv2 pan-cancer AAC -0.1 0.004
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