1. Home/
  2. Compounds/
  3. ruxolitinib

ruxolitinib

Synonyms

SourcesNames Used
GDSC1000Ruxolitinib
CTRPv2ruxolitinib
PharmacoGx ruxolitinib

External IDs

DatabaseIdentifier
Smiles: N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
Pubchem: 25126798

Annotated Targets

JAK2, JAK1, JAK3, TYK2

FDA Approval Status

Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to ruxolitinib


Feature TypeStandardized
Nominal ANOVA
mRNA LCP2 CTRPv2 pan-cancer AAC 0.24 1e-09
mRNA PRF1 GDSC1000 pan-cancer AAC 0.21 1e-09
mRNA AGPAT3 CTRPv2 pan-cancer AAC 0.21 1e-09
mRNA TMEM217 GDSC1000 pan-cancer AAC 0.2 1e-09
mRNA YOD1 CTRPv2 pan-cancer AAC 0.2 1e-09
mRNA GCSAML GDSC1000 pan-cancer AAC 0.2 1e-09
mRNA IL2RB GDSC1000 pan-cancer AAC 0.22 1e-09
mRNA MYO1F GDSC1000 pan-cancer AAC 0.23 2e-09
mRNA TGFB1 CTRPv2 pan-cancer AAC 0.23 2e-09
mRNA GP9 CTRPv2 pan-cancer AAC 0.2 2e-09
Download CSV