1. Home/
  2. Compounds/
  3. ruxolitinib

ruxolitinib

Synonyms

SourcesNames Used
GDSC1000Ruxolitinib
CTRPv2ruxolitinib
PharmacoGx ruxolitinib

External IDs

DatabaseIdentifier
Smiles: N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
Pubchem: 25126798

Annotated Targets

JAK2, JAK1, JAK3, TYK2

FDA Approval Status

Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to ruxolitinib


Feature TypeStandardized
Nominal ANOVA
mRNA CD72 GDSC1000 pan-cancer AAC -0.24 3e-10
mRNA NUTM2D CTRPv2 pan-cancer AAC 0.21 4e-10
mRNA COL20A1 CTRPv2 pan-cancer AAC 0.22 4e-10
mRNA MC5R CTRPv2 pan-cancer AAC 0.2 5e-10
mRNA TRIM6 CTRPv2 pan-cancer AAC 0.22 5e-10
mRNA MEX3B CTRPv2 pan-cancer AAC 0.22 5e-10
mRNA AC006538.4 CTRPv2 pan-cancer AAC 0.24 5e-10
mRNA PLAGL1 CTRPv2 pan-cancer AAC 0.22 5e-10
mRNA PIK3CB CTRPv2 pan-cancer AAC 0.21 6e-10
mRNA PTGDR2 CTRPv2 pan-cancer AAC 0.21 7e-10
Download CSV