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ruxolitinib

Synonyms

SourcesNames Used
GDSC1000Ruxolitinib
CTRPv2ruxolitinib
PharmacoGx ruxolitinib

External IDs

DatabaseIdentifier
Smiles: N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
Pubchem: 25126798

Annotated Targets

JAK2, JAK1, JAK3, TYK2

FDA Approval Status

Approved
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Top molecular features associated with response to ruxolitinib


Feature TypeStandardized
Nominal ANOVA
mRNA SLC18A2 CTRPv2 pan-cancer AAC 0.22 7e-11
mRNA MAPKAPK3 CTRPv2 pan-cancer AAC 0.22 8e-11
mRNA USP48 CTRPv2 pan-cancer AAC 0.25 8e-11
mRNA ITGA2B GDSC1000 pan-cancer AAC 0.21 9e-11
mRNA MYO16 CTRPv2 pan-cancer AAC 0.22 9e-11
mRNA RYR2 GDSC1000 pan-cancer AAC 0.21 1e-10
mRNA FUT1 CTRPv2 pan-cancer AAC 0.22 1e-10
mRNA KCNK6 CTRPv2 pan-cancer AAC 0.22 1e-10
mRNA FAM124B CTRPv2 pan-cancer AAC 0.22 2e-10
mRNA STON2 CTRPv2 pan-cancer AAC 0.22 2e-10
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