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ruxolitinib

Synonyms

SourcesNames Used
GDSC1000Ruxolitinib
CTRPv2ruxolitinib
PharmacoGx ruxolitinib

External IDs

DatabaseIdentifier
Smiles: N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
Pubchem: 25126798

Annotated Targets

JAK2, JAK1, JAK3, TYK2

FDA Approval Status

Approved
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Top molecular features associated with response to ruxolitinib


Feature TypeStandardized
Nominal ANOVA
mRNA LRTM1 CTRPv2 pan-cancer AAC 0.22 3e-11
mRNA OSM CTRPv2 pan-cancer AAC 0.23 3e-11
mRNA TESPA1 CTRPv2 pan-cancer AAC 0.25 3e-11
mRNA GYPE GDSC1000 pan-cancer AAC 0.22 4e-11
mRNA GBGT1 CTRPv2 pan-cancer AAC 0.24 4e-11
mRNA CD27 GDSC1000 pan-cancer AAC -0.24 4e-11
mRNA GRAP GDSC1000 pan-cancer AAC -0.27 5e-11
mRNA HNRNPLL GDSC1000 pan-cancer AAC 0.23 5e-11
mRNA EMID1 CTRPv2 pan-cancer AAC 0.23 6e-11
mRNA GZMH GDSC1000 pan-cancer AAC 0.21 7e-11
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