1. Home/
  2. Compounds/
  3. ruxolitinib

ruxolitinib

Synonyms

SourcesNames Used
GDSC1000Ruxolitinib
CTRPv2ruxolitinib
PharmacoGx ruxolitinib

External IDs

DatabaseIdentifier
Smiles: N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
Pubchem: 25126798

Annotated Targets

JAK2, JAK1, JAK3, TYK2

FDA Approval Status

Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to ruxolitinib


Feature TypeStandardized
Nominal ANOVA
mRNA IL23R CTRPv2 pan-cancer AAC 0.23 7e-12
mRNA CISH CTRPv2 pan-cancer AAC 0.24 7e-12
mRNA BMP2K CTRPv2 pan-cancer AAC 0.25 8e-12
mRNA CD200R1 CTRPv2 pan-cancer AAC 0.23 8e-12
mRNA PRG3 CTRPv2 pan-cancer AAC 0.23 9e-12
mRNA P2RY8 GDSC1000 pan-cancer AAC -0.43 1e-11
mRNA JAK2 GDSC1000 pan-cancer AAC 0.23 1e-11
mRNA APOC1 CTRPv2 pan-cancer AAC 0.23 1e-11
mRNA CD19 GDSC1000 pan-cancer AAC -0.26 1e-11
mRNA HVCN1 GDSC1000 pan-cancer AAC -0.3 1e-11
Download CSV