1. Home/
  2. Compounds/
  3. ruxolitinib

ruxolitinib

Synonyms

SourcesNames Used
GDSC1000Ruxolitinib
CTRPv2ruxolitinib
PharmacoGx ruxolitinib

External IDs

DatabaseIdentifier
Smiles: N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
Pubchem: 25126798

Annotated Targets

JAK2, JAK1, JAK3, TYK2

FDA Approval Status

Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to ruxolitinib


Feature TypeStandardized
Nominal ANOVA
mRNA VPREB3 GDSC1000 pan-cancer AAC -0.26 2e-12
mRNA HPSE2 GDSC1000 pan-cancer AAC 0.23 2e-12
mRNA CKAP4 GDSC1000 pan-cancer AAC -0.31 2e-12
mRNA SPIN4 CTRPv2 pan-cancer AAC 0.24 3e-12
mRNA STXBP5 CTRPv2 pan-cancer AAC 0.23 3e-12
mRNA LY86 GDSC1000 pan-cancer AAC -0.29 4e-12
mRNA MAN2A2 CTRPv2 pan-cancer AAC 0.24 4e-12
mRNA TCL1A GDSC1000 pan-cancer AAC -0.26 4e-12
mRNA TMPRSS11F GDSC1000 pan-cancer AAC 0.22 4e-12
mRNA ICAM5 CTRPv2 pan-cancer AAC 0.24 4e-12
Download CSV