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ruxolitinib

Synonyms

SourcesNames Used
GDSC1000Ruxolitinib
CTRPv2ruxolitinib
PharmacoGx ruxolitinib

External IDs

DatabaseIdentifier
Smiles: N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
Pubchem: 25126798

Annotated Targets

JAK2, JAK1, JAK3, TYK2

FDA Approval Status

Approved
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Top molecular features associated with response to ruxolitinib


Feature TypeStandardized
Nominal ANOVA
mRNA ALAS2 GDSC1000 pan-cancer AAC 0.29 3e-19
mRNA KLF1 CTRPv2 pan-cancer AAC 0.3 1e-18
mRNA MAS1L CTRPv2 pan-cancer AAC 0.29 2e-18
mRNA STARD8 CTRPv2 pan-cancer AAC 0.3 2e-18
mRNA GCSAML CTRPv2 pan-cancer AAC 0.29 5e-18
mRNA SELPLG GDSC1000 pan-cancer AAC 0.35 6e-18
mRNA CMTM5 CTRPv2 pan-cancer AAC 0.28 8e-18
mRNA RCL1 CTRPv2 pan-cancer AAC 0.29 1e-17
mRNA AMHR2 CTRPv2 pan-cancer AAC 0.28 1e-17
mRNA WNT9B CTRPv2 pan-cancer AAC 0.28 1e-17
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