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ruxolitinib

Synonyms

SourcesNames Used
GDSC1000Ruxolitinib
CTRPv2ruxolitinib
PharmacoGx ruxolitinib

External IDs

DatabaseIdentifier
Smiles: N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
Pubchem: 25126798

Annotated Targets

JAK2, JAK1, JAK3, TYK2

FDA Approval Status

Approved
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Top molecular features associated with response to ruxolitinib


Feature TypeStandardized
Nominal ANOVA
mRNA PEAR1 CTRPv2 pan-cancer AAC 0.16 6e-06
mRNA SLC5A10 CTRPv2 pan-cancer AAC -0.17 6e-06
mRNA ZNF560 GDSC1000 pan-cancer AAC 0.15 6e-06
mRNA CCDC69 GDSC1000 pan-cancer AAC -0.19 6e-06
mRNA BLNK CTRPv2 pan-cancer AAC -0.17 6e-06
mRNA GABBR1 CTRPv2 pan-cancer AAC 0.15 6e-06
mRNA LAMTOR1 CTRPv2 pan-cancer AAC 0.15 6e-06
mRNA TRPT1 CTRPv2 pan-cancer AAC -0.16 6e-06
mRNA USP20 GDSC1000 pan-cancer AAC 0.16 6e-06
mRNA TEX2 GDSC1000 pan-cancer AAC 0.16 6e-06
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