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ruxolitinib

Synonyms

SourcesNames Used
GDSC1000Ruxolitinib
CTRPv2ruxolitinib
PharmacoGx ruxolitinib

External IDs

DatabaseIdentifier
Smiles: N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
Pubchem: 25126798

Annotated Targets

JAK2, JAK1, JAK3, TYK2

FDA Approval Status

Approved
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Top molecular features associated with response to ruxolitinib


Feature TypeStandardized
Nominal ANOVA
mRNA C22orf15 CTRPv2 pan-cancer AAC -0.17 5e-06
mRNA CXorf21 GDSC1000 pan-cancer AAC -0.21 5e-06
mRNA POU2F2 GDSC1000 pan-cancer AAC -0.17 5e-06
mRNA SRBD1 CTRPv2 pan-cancer AAC 0.16 5e-06
mRNA IL5 CTRPv2 pan-cancer AAC 0.15 5e-06
mRNA ZSCAN12 CTRPv2 pan-cancer AAC 0.17 5e-06
mRNA PPP2R2B GDSC1000 pan-cancer AAC 0.15 5e-06
mRNA HDC GDSC1000 pan-cancer AAC 0.15 6e-06
mRNA CMTM5 GDSC1000 pan-cancer AAC 0.15 6e-06
mRNA SLAMF6 GDSC1000 pan-cancer AAC -0.17 6e-06
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