1. Home/
  2. Compounds/
  3. ruxolitinib

ruxolitinib

Synonyms

SourcesNames Used
GDSC1000Ruxolitinib
CTRPv2ruxolitinib
PharmacoGx ruxolitinib

External IDs

DatabaseIdentifier
Smiles: N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
Pubchem: 25126798

Annotated Targets

JAK2, JAK1, JAK3, TYK2

FDA Approval Status

Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to ruxolitinib


Feature TypeStandardized
Nominal ANOVA
mRNA FBXO7 CTRPv2 pan-cancer AAC 0.19 4e-06
mRNA NXF3 CTRPv2 pan-cancer AAC 0.16 4e-06
mRNA RALGPS2 CTRPv2 pan-cancer AAC -0.15 5e-06
mRNA KIT GDSC1000 pan-cancer AAC 0.15 5e-06
mRNA ST8SIA6 CTRPv2 pan-cancer AAC 0.15 5e-06
mRNA H1F0 CTRPv2 pan-cancer AAC 0.16 5e-06
mRNA TFEB GDSC1000 pan-cancer AAC -0.17 5e-06
mRNA TLR7 GDSC1000 pan-cancer AAC -0.16 5e-06
mRNA PIP4K2A CTRPv2 pan-cancer AAC 0.18 5e-06
mRNA NR5A1 CTRPv2 pan-cancer AAC 0.15 5e-06
Download CSV