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ruxolitinib

Synonyms

SourcesNames Used
GDSC1000Ruxolitinib
CTRPv2ruxolitinib
PharmacoGx ruxolitinib

External IDs

DatabaseIdentifier
Smiles: N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
Pubchem: 25126798

Annotated Targets

JAK2, JAK1, JAK3, TYK2

FDA Approval Status

Approved
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Top molecular features associated with response to ruxolitinib


Feature TypeStandardized
Nominal ANOVA
mRNA ORAI2 GDSC1000 pan-cancer AAC -0.18 3e-06
mRNA ADGRE3 CTRPv2 pan-cancer AAC 0.16 3e-06
mRNA HIPK2 GDSC1000 pan-cancer AAC 0.17 3e-06
mRNA BCL7A CTRPv2 pan-cancer AAC -0.18 3e-06
mRNA PWP2 CTRPv2 pan-cancer AAC 0.16 3e-06
mRNA AMMECR1 CTRPv2 pan-cancer AAC 0.16 3e-06
mRNA CTB-133G6.1 CTRPv2 pan-cancer AAC -0.2 3e-06
mRNA HTRA2 CTRPv2 pan-cancer AAC 0.18 3e-06
mRNA NCR1 CTRPv2 pan-cancer AAC 0.16 3e-06
mRNA PRSS57 CTRPv2 pan-cancer AAC 0.16 3e-06
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