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ruxolitinib

Synonyms

SourcesNames Used
GDSC1000Ruxolitinib
CTRPv2ruxolitinib
PharmacoGx ruxolitinib

External IDs

DatabaseIdentifier
Smiles: N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
Pubchem: 25126798

Annotated Targets

JAK2, JAK1, JAK3, TYK2

FDA Approval Status

Approved
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Top molecular features associated with response to ruxolitinib


Feature TypeStandardized
Nominal ANOVA
mRNA CARMIL2 CTRPv2 pan-cancer AAC -0.22 1e-06
mRNA PLCXD1 CTRPv2 pan-cancer AAC 0.18 1e-06
mRNA TCF3 CTRPv2 pan-cancer AAC -0.2 1e-06
mRNA MYCT1 CTRPv2 pan-cancer AAC 0.17 1e-06
mRNA SYVN1 CTRPv2 pan-cancer AAC -0.19 1e-06
mRNA KCNN3 GDSC1000 pan-cancer AAC -0.17 1e-06
mRNA GP9 GDSC1000 pan-cancer AAC 0.16 1e-06
mRNA LYN CTRPv2 pan-cancer AAC 0.19 1e-06
mRNA TXN2 CTRPv2 pan-cancer AAC 0.18 1e-06
mRNA CASP3 CTRPv2 pan-cancer AAC 0.18 1e-06
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