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ruxolitinib

Synonyms

SourcesNames Used
GDSC1000Ruxolitinib
CTRPv2ruxolitinib
PharmacoGx ruxolitinib

External IDs

DatabaseIdentifier
Smiles: N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
Pubchem: 25126798

Annotated Targets

JAK2, JAK1, JAK3, TYK2

FDA Approval Status

Approved
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Top molecular features associated with response to ruxolitinib


Feature TypeStandardized
Nominal ANOVA
mRNA TMEM243 GDSC1000 pan-cancer AAC -0.17 9e-07
mRNA PLCB2 CTRPv2 pan-cancer AAC 0.19 9e-07
mRNA VPREB3 CTRPv2 pan-cancer AAC -0.18 9e-07
mRNA RUBCNL GDSC1000 pan-cancer AAC -0.18 9e-07
mRNA WARS CTRPv2 pan-cancer AAC 0.17 1e-06
mRNA N4BP2L1 CTRPv2 pan-cancer AAC 0.21 1e-06
mRNA TSPAN32 GDSC1000 pan-cancer AAC 0.17 1e-06
mRNA TM6SF1 CTRPv2 pan-cancer AAC 0.17 1e-06
mRNA TANC1 CTRPv2 pan-cancer AAC 0.19 1e-06
mRNA CD226 CTRPv2 pan-cancer AAC 0.17 1e-06
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