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ruxolitinib

Synonyms

SourcesNames Used
GDSC1000Ruxolitinib
CTRPv2ruxolitinib
PharmacoGx ruxolitinib

External IDs

DatabaseIdentifier
Smiles: N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
Pubchem: 25126798

Annotated Targets

JAK2, JAK1, JAK3, TYK2

FDA Approval Status

Approved
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Top molecular features associated with response to ruxolitinib


Feature TypeStandardized
Nominal ANOVA
mRNA CDC37L1 CTRPv2 pan-cancer AAC 0.17 8e-07
mRNA CCL17 CTRPv2 pan-cancer AAC 0.16 8e-07
mRNA FAH CTRPv2 pan-cancer AAC 0.17 8e-07
mRNA CLIC2 CTRPv2 pan-cancer AAC 0.17 8e-07
mRNA IL3RA GDSC1000 pan-cancer AAC 0.18 8e-07
mRNA AC004381.6 CTRPv2 pan-cancer AAC 0.17 8e-07
mRNA ADAMTS3 CTRPv2 pan-cancer AAC 0.17 8e-07
mRNA CD84 CTRPv2 pan-cancer AAC 0.2 8e-07
mRNA CEACAM21 CTRPv2 pan-cancer AAC -0.18 9e-07
mRNA CD300C CTRPv2 pan-cancer AAC 0.17 9e-07
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