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ruxolitinib

Synonyms

SourcesNames Used
GDSC1000Ruxolitinib
CTRPv2ruxolitinib
PharmacoGx ruxolitinib

External IDs

DatabaseIdentifier
Smiles: N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
Pubchem: 25126798

Annotated Targets

JAK2, JAK1, JAK3, TYK2

FDA Approval Status

Approved
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Top molecular features associated with response to ruxolitinib


Feature TypeStandardized
Nominal ANOVA
mRNA TTC38 CTRPv2 pan-cancer AAC 0.18 6e-07
mRNA FBP2 CTRPv2 pan-cancer AAC 0.17 6e-07
mRNA ZNF225 CTRPv2 pan-cancer AAC 0.17 6e-07
mRNA SLC12A6 CTRPv2 pan-cancer AAC 0.18 7e-07
mRNA APOL4 GDSC1000 pan-cancer AAC 0.17 7e-07
mRNA LPCAT3 CTRPv2 pan-cancer AAC 0.18 7e-07
mRNA GLOD5 CTRPv2 pan-cancer AAC 0.17 7e-07
mRNA DNASE1 CTRPv2 pan-cancer AAC -0.18 7e-07
mRNA SH2B2 CTRPv2 pan-cancer AAC -0.19 7e-07
mRNA MPL CTRPv2 pan-cancer AAC 0.17 7e-07
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