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ruxolitinib

Synonyms

SourcesNames Used
GDSC1000Ruxolitinib
CTRPv2ruxolitinib
PharmacoGx ruxolitinib

External IDs

DatabaseIdentifier
Smiles: N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
Pubchem: 25126798

Annotated Targets

JAK2, JAK1, JAK3, TYK2

FDA Approval Status

Approved
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Top molecular features associated with response to ruxolitinib


Feature TypeStandardized
Nominal ANOVA
mRNA TIFA GDSC1000 pan-cancer AAC -0.22 5e-07
mRNA HDAC7 CTRPv2 pan-cancer AAC 0.18 5e-07
mRNA PICALM CTRPv2 pan-cancer AAC 0.17 5e-07
mRNA CCR5 GDSC1000 pan-cancer AAC 0.17 6e-07
mRNA MCUB CTRPv2 pan-cancer AAC -0.18 6e-07
mRNA POU2AF1 GDSC1000 pan-cancer AAC -0.22 6e-07
mRNA STXBP5 GDSC1000 pan-cancer AAC 0.16 6e-07
mRNA PARVB CTRPv2 pan-cancer AAC 0.2 6e-07
mRNA CD160 GDSC1000 pan-cancer AAC 0.16 6e-07
mRNA GOLGA8N CTRPv2 pan-cancer AAC 0.18 6e-07
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