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ruxolitinib

Synonyms

SourcesNames Used
GDSC1000Ruxolitinib
CTRPv2ruxolitinib
PharmacoGx ruxolitinib

External IDs

DatabaseIdentifier
Smiles: N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
Pubchem: 25126798

Annotated Targets

JAK2, JAK1, JAK3, TYK2

FDA Approval Status

Approved
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Top molecular features associated with response to ruxolitinib


Feature TypeStandardized
Nominal ANOVA
mRNA MLLT3 GDSC1000 pan-cancer AAC 0.18 1e-07
mRNA ACSM3 CTRPv2 pan-cancer AAC 0.18 1e-07
mRNA BATF CTRPv2 pan-cancer AAC 0.19 2e-07
mRNA E2F2 CTRPv2 pan-cancer AAC -0.21 2e-07
mRNA IL3 CTRPv2 pan-cancer AAC 0.17 2e-07
mRNA BLK CTRPv2 pan-cancer AAC -0.2 2e-07
mRNA IPO11 CTRPv2 pan-cancer AAC 0.17 2e-07
mRNA SMARCA2 CTRPv2 pan-cancer AAC 0.19 2e-07
mRNA STAT5A CTRPv2 pan-cancer AAC 0.2 2e-07
mRNA RD3L CTRPv2 pan-cancer AAC 0.17 2e-07
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