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ruxolitinib

Synonyms

SourcesNames Used
GDSC1000Ruxolitinib
CTRPv2ruxolitinib
PharmacoGx ruxolitinib

External IDs

DatabaseIdentifier
Smiles: N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
Pubchem: 25126798

Annotated Targets

JAK2, JAK1, JAK3, TYK2

FDA Approval Status

Approved
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Top molecular features associated with response to ruxolitinib


Feature TypeStandardized
Nominal ANOVA
mRNA CH507-9B2.5 CTRPv2 pan-cancer AAC 0.19 1e-07
mRNA TTLL10 CTRPv2 pan-cancer AAC 0.18 1e-07
mRNA APOE CTRPv2 pan-cancer AAC 0.18 1e-07
mRNA BCAS4 GDSC1000 pan-cancer AAC -0.18 1e-07
mRNA RGS6 CTRPv2 pan-cancer AAC 0.18 1e-07
mRNA ADORA2A CTRPv2 pan-cancer AAC -0.2 1e-07
mRNA PPP3R1 CTRPv2 pan-cancer AAC 0.19 1e-07
mRNA IL2RA CTRPv2 pan-cancer AAC 0.18 1e-07
mRNA CA8 CTRPv2 pan-cancer AAC 0.18 1e-07
mRNA TMEM243 CTRPv2 pan-cancer AAC -0.19 1e-07
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