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ruxolitinib

Synonyms

SourcesNames Used
GDSC1000Ruxolitinib
CTRPv2ruxolitinib
PharmacoGx ruxolitinib

External IDs

DatabaseIdentifier
Smiles: N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
Pubchem: 25126798

Annotated Targets

JAK2, JAK1, JAK3, TYK2

FDA Approval Status

Approved
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Top molecular features associated with response to ruxolitinib


Feature TypeStandardized
Nominal ANOVA
mRNA TFR2 GDSC1000 pan-cancer AAC 0.18 8e-08
mRNA DTX1 GDSC1000 pan-cancer AAC -0.2 8e-08
mRNA RHEBL1 CTRPv2 pan-cancer AAC 0.2 8e-08
mRNA SNX22 GDSC1000 pan-cancer AAC -0.19 8e-08
mRNA DNAAF3 CTRPv2 pan-cancer AAC 0.18 8e-08
mRNA ITGAM GDSC1000 pan-cancer AAC 0.18 8e-08
mRNA C6orf25 GDSC1000 pan-cancer AAC 0.18 9e-08
mRNA SYVN1 GDSC1000 pan-cancer AAC -0.19 9e-08
mRNA GLUL CTRPv2 pan-cancer AAC 0.18 9e-08
mRNA RILP CTRPv2 pan-cancer AAC 0.18 1e-07
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