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ruxolitinib

Synonyms

SourcesNames Used
GDSC1000Ruxolitinib
CTRPv2ruxolitinib
PharmacoGx ruxolitinib

External IDs

DatabaseIdentifier
Smiles: N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
Pubchem: 25126798

Annotated Targets

JAK2, JAK1, JAK3, TYK2

FDA Approval Status

Approved
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Top molecular features associated with response to ruxolitinib


Feature TypeStandardized
Nominal ANOVA
mRNA CCDC105 CTRPv2 pan-cancer AAC 0.18 3e-08
mRNA RFESD GDSC1000 pan-cancer AAC 0.19 3e-08
mRNA BLNK GDSC1000 pan-cancer AAC -0.21 3e-08
mRNA DKC1 CTRPv2 pan-cancer AAC 0.19 4e-08
mRNA TAL1 GDSC1000 pan-cancer AAC 0.18 4e-08
mRNA RGS18 CTRPv2 pan-cancer AAC 0.2 4e-08
mRNA AC015688.3 CTRPv2 pan-cancer AAC 0.21 4e-08
mRNA ABHD5 GDSC1000 pan-cancer AAC 0.18 4e-08
mRNA PAX5 GDSC1000 pan-cancer AAC -0.21 4e-08
mRNA HBD GDSC1000 pan-cancer AAC 0.18 5e-08
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