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ruxolitinib

Synonyms

SourcesNames Used
GDSC1000Ruxolitinib
CTRPv2ruxolitinib
PharmacoGx ruxolitinib

External IDs

DatabaseIdentifier
Smiles: N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
Pubchem: 25126798

Annotated Targets

JAK2, JAK1, JAK3, TYK2

FDA Approval Status

Approved
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Top molecular features associated with response to ruxolitinib


Feature TypeStandardized
Nominal ANOVA
mRNA GAB3 GDSC1000 pan-cancer AAC 0.22 2e-08
mRNA IFNGR2 GDSC1000 pan-cancer AAC -0.18 3e-08
mRNA AICDA GDSC1000 pan-cancer AAC -0.19 3e-08
mRNA UBAC1 CTRPv2 pan-cancer AAC 0.19 3e-08
mRNA TFRC CTRPv2 pan-cancer AAC 0.18 3e-08
mRNA CD52 GDSC1000 pan-cancer AAC -0.25 3e-08
mRNA FAM19A2 CTRPv2 pan-cancer AAC 0.19 3e-08
mRNA RAB6B CTRPv2 pan-cancer AAC 0.19 3e-08
mRNA ADCY7 CTRPv2 pan-cancer AAC 0.2 3e-08
mRNA OR13A1 GDSC1000 pan-cancer AAC -0.19 3e-08
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