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ruxolitinib

Synonyms

SourcesNames Used
GDSC1000Ruxolitinib
CTRPv2ruxolitinib
PharmacoGx ruxolitinib

External IDs

DatabaseIdentifier
Smiles: N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
Pubchem: 25126798

Annotated Targets

JAK2, JAK1, JAK3, TYK2

FDA Approval Status

Approved
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Top molecular features associated with response to ruxolitinib


Feature TypeStandardized
Nominal ANOVA
mRNA ZNF146 CTRPv2 pan-cancer AAC 0.2 1e-08
mRNA HPS1 CTRPv2 pan-cancer AAC 0.21 1e-08
mRNA GMPR CTRPv2 pan-cancer AAC 0.2 1e-08
mRNA HAVCR2 CTRPv2 pan-cancer AAC 0.19 1e-08
mRNA RNF213 GDSC1000 pan-cancer AAC 0.19 1e-08
mRNA RCSD1 GDSC1000 pan-cancer AAC -0.31 1e-08
mRNA BACH2 GDSC1000 pan-cancer AAC -0.2 1e-08
mRNA DUSP21 CTRPv2 pan-cancer AAC 0.19 2e-08
mRNA BFSP2 GDSC1000 pan-cancer AAC -0.21 2e-08
mRNA CLCN4 CTRPv2 pan-cancer AAC 0.19 2e-08
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