1. Home/
  2. Compounds/
  3. ruxolitinib

ruxolitinib

Synonyms

SourcesNames Used
GDSC1000Ruxolitinib
CTRPv2ruxolitinib
PharmacoGx ruxolitinib

External IDs

DatabaseIdentifier
Smiles: N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
Pubchem: 25126798

Annotated Targets

JAK2, JAK1, JAK3, TYK2

FDA Approval Status

Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to ruxolitinib


Feature TypeStandardized
Nominal ANOVA
mRNA RP11-119J18.1 CTRPv2 pan-cancer AAC 0.2 7e-09
mRNA PLPP6 GDSC1000 pan-cancer AAC 0.2 8e-09
mRNA ICAM4 CTRPv2 pan-cancer AAC 0.19 8e-09
mRNA GCSAM GDSC1000 pan-cancer AAC -0.23 9e-09
mRNA IL9 GDSC1000 pan-cancer AAC 0.18 9e-09
mRNA IL13 CTRPv2 pan-cancer AAC 0.19 9e-09
mRNA SIGLECL1 GDSC1000 pan-cancer AAC 0.19 1e-08
mRNA MPP1 CTRPv2 pan-cancer AAC 0.2 1e-08
mRNA CD7 GDSC1000 pan-cancer AAC 0.19 1e-08
mRNA FECH CTRPv2 pan-cancer AAC 0.2 1e-08
Download CSV