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ruxolitinib

Synonyms

SourcesNames Used
GDSC1000Ruxolitinib
CTRPv2ruxolitinib
PharmacoGx ruxolitinib

External IDs

DatabaseIdentifier
Smiles: N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
Pubchem: 25126798

Annotated Targets

JAK2, JAK1, JAK3, TYK2

FDA Approval Status

Approved
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Top molecular features associated with response to ruxolitinib


Feature TypeStandardized
Nominal ANOVA
mRNA GNG7 GDSC1000 pan-cancer AAC -0.24 4e-09
mRNA ISPD CTRPv2 pan-cancer AAC 0.2 4e-09
mRNA RGS6 GDSC1000 pan-cancer AAC 0.2 4e-09
mRNA COL6A5 CTRPv2 pan-cancer AAC 0.2 4e-09
mRNA NTRK1 GDSC1000 pan-cancer AAC 0.2 4e-09
mRNA SLC39A3 CTRPv2 pan-cancer AAC 0.22 5e-09
mRNA KEL GDSC1000 pan-cancer AAC 0.19 5e-09
mRNA MYL4 GDSC1000 pan-cancer AAC 0.2 5e-09
mRNA TRIM10 CTRPv2 pan-cancer AAC 0.19 5e-09
mRNA EPB42 GDSC1000 pan-cancer AAC 0.19 5e-09
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