1. Home/
  2. Compounds/
  3. ruxolitinib

ruxolitinib

Synonyms

SourcesNames Used
GDSC1000Ruxolitinib
CTRPv2ruxolitinib
PharmacoGx ruxolitinib

External IDs

DatabaseIdentifier
Smiles: N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
Pubchem: 25126798

Annotated Targets

JAK2, JAK1, JAK3, TYK2

FDA Approval Status

Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to ruxolitinib


Feature TypeStandardized
Nominal ANOVA
mRNA RSPO4 GDSC1000 pan-cancer AAC 0.096 0.003
mRNA ANK1 GDSC1000 pan-cancer AAC 0.096 0.003
mRNA PHKA1 GDSC1000 pan-cancer AAC 0.1 0.003
mRNA STXBP6 GDSC1000 pan-cancer AAC 0.1 0.003
mRNA NARFL GDSC1000 pan-cancer AAC -0.1 0.003
mRNA UBE2F CTRPv2 pan-cancer AAC 0.1 0.003
mRNA ZNF784 GDSC1000 pan-cancer AAC 0.097 0.003
mRNA WDR19 CTRPv2 pan-cancer AAC -0.1 0.003
mRNA CCDC134 GDSC1000 pan-cancer AAC 0.098 0.003
mRNA ZNF844 CTRPv2 pan-cancer AAC 0.1 0.003
Download CSV