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ruxolitinib

Synonyms

SourcesNames Used
GDSC1000Ruxolitinib
CTRPv2ruxolitinib
PharmacoGx ruxolitinib

External IDs

DatabaseIdentifier
Smiles: N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
Pubchem: 25126798

Annotated Targets

JAK2, JAK1, JAK3, TYK2

FDA Approval Status

Approved
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Top molecular features associated with response to ruxolitinib


Feature TypeStandardized
Nominal ANOVA
mRNA IL15 GDSC1000 pan-cancer AAC 0.1 0.003
mRNA UHRF1 CTRPv2 pan-cancer AAC -0.11 0.003
mRNA FN3K CTRPv2 pan-cancer AAC 0.1 0.003
mRNA CSN1S1 GDSC1000 pan-cancer AAC -0.095 0.003
mRNA JPH3 GDSC1000 pan-cancer AAC 0.099 0.003
mRNA DCLRE1A GDSC1000 pan-cancer AAC 0.1 0.003
mRNA AGPAT4 CTRPv2 pan-cancer AAC 0.11 0.003
mRNA GATA2 GDSC1000 pan-cancer AAC 0.11 0.003
mRNA SYCP2L GDSC1000 pan-cancer AAC 0.098 0.003
mRNA SDR39U1 CTRPv2 pan-cancer AAC -0.11 0.003
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